Shaoxiong Yang1, Yingxin Qi2, Zonglai Jiang2, Xiaobo Gong1,*
Molecular & Cellular Biomechanics, Vol.16, No.1, pp. 13-26, 2019, DOI:10.32604/mcb.2019.06096
Abstract Vascular diseases during aging process are closely correlated to the age-related changes of mechanical stimuli for resident cells. Characterizing the variations of mechanical environments in vessel walls with advancing age is crucial for a better understanding of vascular remodeling and pathological changes. In this study, the mechanical stress, strain, and wall stiffness of the femoropopliteal arteries (FPAs) were compared among four different age groups from adolescent to young, middle-aged, and aged subjects. The material parameters and geometries adopted in the FPA models were obtained from published experimental results. It is found that high mechanical stress appears at different layers in… More >
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