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    ARTICLE

    Patient-Specific Echo-Based Fluid-Structure Interaction Modeling Study of Blood Flow in the Left Ventricle with Infarction and Hypertension

    Longling Fan1,*, Jing Yao 2, *, Chun Yang3, Di Xu2, Dalin Tang1, 4, §

    CMES-Computer Modeling in Engineering & Sciences, Vol.114, No.2, pp. 221-237, 2018, DOI:10.3970/cmes.2018.114.221

    Abstract Understanding cardiac blood flow behaviors is of importance for cardiovascular research and clinical assessment of ventricle functions. Patient-specific Echo-based left ventricle (LV) fluid-structure interaction (FSI) models were introduced to perform ventricle mechanical analysis, investigate flow behaviors, and evaluate the impact of myocardial infarction (MI) and hypertension on blood flow in the LV. Echo image data were acquired from 3 patients with consent obtained: one healthy volunteer (P1), one hypertension patient (P2), and one patient who had an inferior and posterior myocardial infarction (P3). The nonlinear Mooney-Rivlin model was used for ventricle tissue with material parameter values chosen to match echo-measure… More >

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