Laura S. Kverneland1,2, Peter Kramer2, Stanislav Ovroutski2
Congenital Heart Disease, Vol.13, No.2, pp. 181-193, 2018, DOI:10.1111/chd.12570
Abstract Almost fifty years after its first clinical application, the modified Fontan operation is among the
most frequently performed procedures in congenital heart disease surgery in children today. The
objective of this review is to systematically summarize the international evolution of outcomes in
regard to morbidity and mortality of patients with Fontan palliation. All studies published over the
past five decades with more than 100 Fontan patients included were screened. In eligible studies,
information concerning preoperative patients’ characteristics, Fontan modifications employed,
early mortality, long-term survival and frequency of relevant complications was extracted. Ultimately, thirty-one studies published by the largest surgical centers… More >
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