Omnia Shafei1,2,*, Alyaa A. Kotby1,2, Mona M. El Ganzoury1,2, Nevin M. Habeeb1,2, Eman Elsayed1,2
Congenital Heart Disease, Vol.17, No.2, pp. 173-185, 2022, DOI:10.32604/CHD.2021.016987
Abstract Objectives: We aimed to evaluate the effect of percutaneous atrial septal defect (ASD) closure in children using
right heart indices and serum galectin-3 (Gal-3), as potential biomarkers of right heart remodeling. Methods: This
case–control prospective study included 40 children with ASD and 25 control subjects. An echocardiographic evaluation was performed before the procedure, as well as 24 h, 1 month, and 6 months after intervention. Serum
Gal-3 was measured before, and 1 month after the procedure. Results: Serum Gal-3 concentration, right atrial
(RA) dimensions, right ventricular (RV) dimensions, indexed RA area, and right index of myocardial
performance (RIMP) were significantly… More >
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