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  • Open Access

    ARTICLE

    Biostimulatory Influence of Commercial Seaweed Extract on Seed Emergence, Seedling Growth, and Vigor of Winter Rice

    Zakia Akter1, Sumona Akter Jannat2, Sheikh Md. Shibly1, Afroza Sultana1, Amdadul Hoque Amran1, Joairia Hossain Faria1, Sabina Yeasmin1, Md. Parvez Anwar1,*

    Phyton-International Journal of Experimental Botany, Vol.95, No.1, 2026, DOI:10.32604/phyton.2026.075524 - 30 January 2026

    Abstract Seaweed extract contains plant growth regulators and bio-stimulants that enhance plant growth and development. In Bangladesh, winter rice (Boro rice) in the nursery bed often shows poor seed emergence and weak seedling growth due to low temperature. This problem can be addressed by using seaweed extract as a seed priming agent and bio-stimulant. The objective of this study was to evaluate the effectiveness of seaweed extract (Crop Plus) on seed emergence, seedling growth, and vigor of winter rice in the nursery. Two experiments were conducted at Bangladesh Agricultural University using BRRI dhan89. The laboratory experiment… More >

  • Open Access

    ARTICLE

    Growth and Yield Responses of Soledad Chili Pepper (Capsicum annuum L.) to the Application of Chitosan and Bacillus subtilis

    Adolfo Amador Mendoza1,*, Rosalba Guadalupe Gomez Raymundo2, Ana Rosa Ramírez Seañez1, Hipolito Hernández Hernández1, Rogelio Enrrique Palacios Torres1, Nelda Xanath Martínez Galero3, Miguel Ángel García Muñoz3, Saribel Zilli Gutiérrez4,*

    Phyton-International Journal of Experimental Botany, Vol.95, No.1, 2026, DOI:10.32604/phyton.2025.073856 - 30 January 2026

    Abstract The cultivation of Soledad pepper (Capsicum annuum L.) is essential in Oaxaca and Veracruz, but it faces issues with pests and diseases, which affect yield and cause economic losses. To mitigate these impacts, farmers have started using biostimulants such as chitosan and plant growth promoting bacteria instead of agrochemicals due to their environmental and health benefits. This study evaluated the effect of Bacillus subtilis and chitosan, both individually and combined, on the growth, yield, and fruit quality of Soledad pepper under greenhouse conditions. Four treatments were applied at different stages of the crop cycle: Q (Chitosan), BS (Bacillus More >

  • Open Access

    ARTICLE

    Impacts of Fertilization and Soil Amendments on Rhizosphere Microbiota and Growth of Panax: A Meta-Analysis

    Hong Chen1,2, Runze Yang1,2, Jing Tian1,2, Boyuan Xu1,2, Qiang Chen3, Yuzong Chen1,2, Ming-Xiao Zhao1,2,*

    Phyton-International Journal of Experimental Botany, Vol.95, No.1, 2026, DOI:10.32604/phyton.2025.072276 - 30 January 2026

    Abstract Panax species are globally recognized for their high medicinal and economic value, yet large-scale cultivation is constrained by high production costs, progressive soil acidification, and persistent soil-borne diseases. Although various soil improvement strategies have been tested, a comprehensive synthesis of their comparative effectiveness has been lacking. Here, we conducted a meta-analysis of 1381 observations from 54 independent studies to evaluate the effects of conventional fertilizers, microbial fertilizers, organic amendments, and inorganic amendments on Panax cultivation. Our results demonstrate that microbial fertilizers, organic amendments, and inorganic amendments significantly increased soil pH, thereby ameliorating soil acidification. Among them,… More >

  • Open Access

    REVIEW

    Progression on Mechanism and Therapeutic Implications of Neddylation in Lung Cancer

    Jiayu Zou1,2,3, Yajie Lu3, Jiaqi Li3, Zhaokai Zhou4,5, Fu Peng3, Pu Qiu2,*, Hailin Tang6, Cheng Peng1,*

    Oncology Research, Vol.34, No.2, 2026, DOI:10.32604/or.2025.071940 - 19 January 2026

    Abstract Lung cancer is the most common but fatal malignant tumor worldwide. Patients with lung cancer experienced a relatively low 5-year overall survival rate, and issues such as metastasis and drug resistance remain prominent challenges in its clinical management. Neddylation, a novel type of post-translational modification, was overactivated in lung cancer and was closely associated with its occurrence, development, metastasis, and drug resistance. This review systematically summarizes the biological process of neddylation and deeply explores the latest research progress on how neddylation affects lung cancer cell proliferation, metastasis, and drug resistance mechanisms, with a focus on More >

  • Open Access

    REVIEW

    A Holistic Review of Oncological Drug Targets and Trajectories of Resistance in Cancer Therapy

    Harpreet Kaur1,*, Dhrubalochan Rana2, Sowvik Bag2, Paramjeet Singh3

    Oncology Research, Vol.34, No.2, 2026, DOI:10.32604/or.2025.071209 - 19 January 2026

    Abstract The prolonged and intricate history of oncological treatments has transitioned significantly since the introduction of chemotherapy. Substantial therapeutic benefits in cancer therapy have been achieved by the integration of conventional treatments with molecular biosciences and omics technologies. Human epidermal growth factor receptor, hormone receptors, and angiogenesis factors are among the established therapies in tumor reduction and managing side effects. Novel targeted therapies like KRAS G12C, Claudin-18 isoform 2 (CLDN18.2), Trophoblast cell-surface antigen 2 (TROP2), and epigenetic regulators emphasize their promise in advancing precision medicine. However, in many cases, the resistance mechanisms associated with these interventions… More > Graphic Abstract

    A Holistic Review of Oncological Drug Targets and Trajectories of Resistance in Cancer Therapy

  • Open Access

    ARTICLE

    Real-World Outcomes of First-Line Palbociclib Plus Endocrine Therapy for HR+/HER2− Metastatic Breast Cancer in Japan: A Single-Center Retrospective Study

    Keiko Yanagihara1,*, Masato Yoshida2, Kensaku Awaji2, Tamami Yamakawa1, Sena Kato1, Miki Tamura1, Koji Nagata3

    Oncology Research, Vol.34, No.1, 2026, DOI:10.32604/or.2025.073891 - 30 December 2025

    Abstract Background: Cyclin-dependent kinase 4/6 (CDK4/6) inhibitors have transformed the management of hormone receptor–positive/HER2–negative (HR+/HER2–) advanced breast cancer, yet evidence for elderly or poor-performance patients remains limited. This study examined real-world outcomes of palbociclib plus endocrine therapy in Asian patients, with additional subgroup analyses by age and performance status. Methods: We retrospectively analyzed 46 consecutive Asian patients with recurrent or de novo HR+/HER2− breast cancer treated with first-line palbociclib plus ET between April 2021 and March 2025. The primary endpoint was progression-free survival (PFS). Secondary endpoints included overall response rate (ORR), disease control rate (DCR), and safety.… More >

  • Open Access

    ARTICLE

    Effect of Fin Spacing on Frost Growth and Airflow Dynamics in ASHP Evaporators

    Zhengqing Zhang1,2,3,*, Xiaojun Yuan2, Hui Wu2

    FDMP-Fluid Dynamics & Materials Processing, Vol.21, No.12, pp. 2927-2943, 2025, DOI:10.32604/fdmp.2025.071115 - 31 December 2025

    Abstract Frost accumulation on the evaporator fins of air source heat pumps (ASHPs) severely degrades heat transfer performance and overall system efficiency. To address this, the present study employs computational fluid dynamics (CFD) to investigate how fin spacing influences frosting behavior, emphasizing the coupled evolution of frost thickness, density, airflow, and temperature distribution within fin channels. Results reveal that fin spacing is a key parameter governing both the extent and rate of frost growth. Wider fin spacing enhances frost accumulation, with a final frost mass of 6.41 g at 12 mm, about 71.8% higher than at More >

  • Open Access

    ARTICLE

    Melatonin Priming Enhances Potassium Dichromate Stress Tolerance and Morpho-Physiological Performance via Genetic Modulation in Melon (Cucumis melo L.) Plant

    Tai Liu1,#, Huichun Xu1,#, Sikandar Amanullah2,*, Ye Che1, Ling Zhang1, Zeyu Jiang1, Weiyi Bi1, Lei Zhu1, Di Wang1,*

    Phyton-International Journal of Experimental Botany, Vol.94, No.12, pp. 4117-4137, 2025, DOI:10.32604/phyton.2025.074131 - 29 December 2025

    Abstract Heavy metal accumulation in agricultural soil is primarily driven by pesticides, polluted water, and industrial gas emissions, which pose threats to sustainable crop production. Chromium (Cr) stress has an adverse impact on plant development and metabolism, but approaches to reduce its toxicity and enhance plant resistance remain limited. Melatonin is a potent antioxidant involved in regulating various morpho-physiological functions of plants under different abiotic stresses. In this study, we investigated the impact of exogenous melatonin to mitigate the negative effects of potassium dichromate (PD) stress in melon plants and analyzed genetic modulation of morphological, physiological,… More >

  • Open Access

    ARTICLE

    Synergistic Effects of Melatonin and Methyl Jasmonate in Mitigating Drought-Induced Oxidative Stress in Common Bean (Phaseolus vulgaris)

    Totan Kumar Ghosh1, Md. Roushonuzzaman Rakib1, Munna1, S. M. Zubair AL-Meraj1, Md. Moshiul Islam2, Anika Nazran1, Mohammad Golam Mostofa3,*

    Phyton-International Journal of Experimental Botany, Vol.94, No.12, pp. 3925-3943, 2025, DOI:10.32604/phyton.2025.073382 - 29 December 2025

    Abstract The productivity of common bean (Phaseolus vulgaris L.), an economically important legume, is severely hindered by drought stress. While melatonin (Mel) and methyl jasmonate (MeJA) are known to alleviate abiotic stresses, their combined effects in mitigating drought-induced oxidative stress are unknown. Here, we examined the synergistic effects of Mel and MeJA in alleviating drought-associated oxidative damage in common bean. Compared with well-watered controls, drought stress caused a significant decline in plant biomass, photosynthetic pigments, and photosystem II efficiency (Fv/Fm). Drought also significantly increased hydrogen peroxide (H2O2) accumulation, which likely contributed to membrane lipid peroxidation, as indicated by… More >

  • Open Access

    ARTICLE

    Chitosan-Selenate Complex Improves Bioactive Profile and Antioxidant Response in Wheat Sprouts (Triticum aestivum L.)

    Jazmín Montserrat Gaucin-Delgado1, Cristian Oswaldo Solis-López2, Pablo Preciado-Rangel3, Bernardo Espinosa-Palomeque4, Francisco Gerardo Veliz-Deras2, Viridiana Contreras-Villarreal2, Ricardo Israel Ramírez-Gottfried5,*

    Phyton-International Journal of Experimental Botany, Vol.94, No.12, pp. 3961-3973, 2025, DOI:10.32604/phyton.2025.072536 - 29 December 2025

    Abstract Selenium (Se) deficiency is a global health problem affecting more than 500 million people; crop biofortification is a sustainable strategy for its mitigation. This study investigated the effect of the application of selenate nanoparticles (SeO42−) and the combination of selenate (SeO42−) and chitosan (CS) (forming a SeO42−-CS complex) on the antioxidant profile, growth, biomass, bioactive compounds, enzymes, and Se accumulation of wheat (Triticum spp.) sprouts. Fourteen treatments were applied using a factorial design combining seven concentrations and two formulations: SeO42− and SeO42−-CS. It was identified that chitosan increased Se uptake efficiency by 30% versus conventional selenate. The optimal… More >

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