Nada Zaari Jabri¹, Mohamed Ait-El-Mokhtar^1,*, Fadoua Mekkaoui¹, Najwa Rabah¹, Ilham Amghar¹, Ghizlane Diria², Abdelaziz Hmyene¹

Phyton-International Journal of Experimental Botany, Vol.94, No.11, pp. 3687-3701, 2025, DOI:10.32604/phyton.2025.071634 - 01 December 2025

Abstract Cadmium (Cd) contamination is a major environmental stressor that adversely affects crop germination and early development. This study assessed the impact of increasing Cd concentrations (0.125 to 1 g/L) on seed germination and early seedling growth in three bread wheat (Triticum aestivum L.) cultivars: Achtar, Lina, and Snina. The results revealed a clear dose-dependent inhibitory effect of Cd. Germination percentage (GP) significantly declined with increasing Cd levels, while mean germination time was progressively delayed, particularly at higher concentrations. Vigor index (VI) also showed significant reductions, reflecting compromised seedling establishment. Morphological traits, especially shoot and root lengths,… More >

Fang Liao, Xiurong Wang^*, Muyan Xie, Lixin Duan

Phyton-International Journal of Experimental Botany, Vol.94, No.11, pp. 3667-3686, 2025, DOI:10.32604/phyton.2025.069653 - 01 December 2025

Abstract Bryophytes play important ecological roles in terrestrial ecosystems, but their growth is often influenced by environmental factors and chemical interactions with surrounding vegetation. Fallen leaves are an important source of allelopathic substances, yet little is known about their impact on mosses. This study investigates the allelopathic effects of fallen leaves from Cinnamomum camphora, Pinus massoniana, and Bambusa emeiensis on the bryophyte Thuidium kanedae in Guiyang. The litter aqueous extract (0.0125 g/mL (T1), 0.025 g/mL (T2), 0.05 g/mL (T3), 0.1 g/mL (T4) and distilled water control (CK)) was used to regularly water and culture T. kanedae. During the 120-day test period,… More >

Yuri A. Piven¹, Danila V. Sorokin², Nastassia A. Varabyeva¹, Alexandra L. Mikhaylova², Fedor B. Bogdanov², Elena V. Shafranovskaya¹, Raman M. Puzanau³, Fedor A. Lakhvich¹, Alexander M. Scherbakov^2,4,*

Oncology Research, Vol.33, No.12, pp. 4049-4072, 2025, DOI:10.32604/or.2025.067832 - 27 November 2025

Abstract Background: The most aggressive forms of breast cancer are characterized by independence from steroid hormones but a strong dependence on growth factors. In such cancer cells, oncogenic receptors, including human epidermal growth factor receptor 2 (HER2), are activated, and their targeted inhibition represents an attractive therapeutic strategy. The study aimed to develop small-molecule potential dual heat shock protein 90 (HSP90)-HER2 inhibitors and evaluate them as anticancer agents in HER2-positive cells. Methods: The research project involved obtaining a series of compounds with potential dual inhibitory activity against HSP90 and HER2 by targeted organic synthesis, which was… More > Graphic Abstract

Hao Yue¹, Di Gao², Jin Gao¹, Chengmei Wei¹, Jiali Duan³, Shaocheng Mei^3,*

Energy Engineering, Vol.122, No.12, pp. 5091-5109, 2025, DOI:10.32604/ee.2025.069140 - 27 November 2025

Abstract Against the backdrop of regional coordinated development and China’s “dual carbon” strategic objectives, the Beijing-Tianjin-Hebei (BTH) region faces an urgent need to transition from its traditional economic growth model, which is heavily reliant on resource consumption. This study investigates the decoupling dynamics among economic growth, energy consumption, and carbon emissions in the BTH region, along with the underlying driving forces, aiming to provide valuable insights for achieving the “dual carbon” targets and fostering high-quality regional development. First, the Tapio decoupling model is employed to analyze the decoupling relationships between economic growth, energy consumption, and carbon… More >

Božo Damjanović^*, Pejo Konjatić, Marko Katinić

CMES-Computer Modeling in Engineering & Sciences, Vol.145, No.2, pp. 1735-1753, 2025, DOI:10.32604/cmes.2025.072256 - 26 November 2025

Abstract Ensuring the structural integrity of piping systems is crucial in industrial operations to prevent catastrophic failures and minimize shutdown time. This study investigates a transportation-damaged pipe exposed to high-temperature conditions and cyclic loading, representing a realistic challenge in plant operation. The objective was to evaluate the service life and integrity assessment parameters of the damaged pipe, subjected to 22,000 operational cycles under two daily charge and discharge conditions. The flaw size in the damaged pipe was determined based on a failure assessment procedure, ensuring a conservative and reliable input. The damage was characterized as a… More >

Abdulnaser M. Alshoaibi^*, Yahya Ali Fageehi

CMES-Computer Modeling in Engineering & Sciences, Vol.145, No.1, pp. 189-214, 2025, DOI:10.32604/cmes.2025.071583 - 30 October 2025

Abstract Fatigue crack growth is a critical phenomenon in engineering structures, accounting for a significant percentage of structural failures across various industries. Accurate prediction of crack initiation, propagation paths, and fatigue life is essential for ensuring structural integrity and optimizing maintenance schedules. This paper presents a comprehensive finite element approach for simulating two-dimensional fatigue crack growth under linear elastic conditions with adaptive mesh generation. The source code for the program was developed in Fortran 95 and compiled with Visual Fortran. To achieve high-fidelity simulations, the methodology integrates several key features: it employs an automatic, adaptive meshing… More >

Ceren Ayşe Bayram^*

Phyton-International Journal of Experimental Botany, Vol.94, No.10, pp. 3283-3295, 2025, DOI:10.32604/phyton.2025.073047 - 29 October 2025

Abstract In semi-arid regions where climatic limitations hinder open-field vegetable production, greenhouse-based lettuce (Lactuca sativa L.) cultivation plays a vital role in ensuring off-season supply. In this study, the potential of sustainable input combinations was evaluated to enhance lettuce productivity, quality, and profitability under unheated greenhouse conditions in Southeastern Türkiye. Treatments included farmer practice and a mycorrhizal biofertilizer (ERS, a water-soluble arbuscular mycorrhizal fungus product) applied alone or in combination with organic-based biostimulants (IS and NM). Evaluated parameters were plant height, leaf pigmentation (a*, h°), SPAD values, vitamin C, nitrogen and phosphorus content, and gross margin. The More >

Xiaomei He¹, Xiaoting Wan¹, Muhammad Arif ², Ziyang Hu¹, Haiyu Wang¹, Muhammad Aamir Manzoor^3,*, Cheng Song^1,*

Phyton-International Journal of Experimental Botany, Vol.94, No.10, pp. 2985-3002, 2025, DOI:10.32604/phyton.2025.070697 - 29 October 2025

Abstract Melatonin is a multifunctional molecule found in all organisms that has been shown to play a crucial role in plant growth, development, and stress response. Plant melatonin is typically synthesized in organelles termed chloroplasts, and the mechanisms of its synthesis and metabolic pathways have been extensively studied. Melatonin serves a significant regulatory function in plant growth and development, influencing the morphological and physiological characteristics of plants by modulating biological processes. While studies on plant melatonin receptors are in their early stages compared to studies in animal receptors, the binding mechanism with melatonin is now recognized… More >

Mingxin Zhong^1,#, Yuanyuan Zhang^1,#, Xinlei Guo¹, Bainian Zhang², Chengjia Tan¹, Zhuo Xu¹, Xin Hu¹, Daren Feng³, Zhenpeng Xi⁴, Qian Wang^1,*, Hui Tian^1,*

Phyton-International Journal of Experimental Botany, Vol.94, No.10, pp. 3061-3084, 2025, DOI:10.32604/phyton.2025.070560 - 29 October 2025

Abstract Magnolia officinalis is a perennial deciduous tree that has medicinal properties. The AP2/ERF gene family has a number of roles in long-term growth and metabolism. The expression of this function varies with the growth period. In this work, based on the transcriptome data of Magnolia officinalis, the complete coding gene of Magnolia officinalis was obtained, and the corresponding protein sequence was retrieved from NCBI and compared with the model plant Arabidopsis thaliana. After screening, 75 protein sequences from the AP2/ERF gene family were identified and called MoAP2/ERF1–MoAP2/ERF75, followed by bioinformatics analysis. 75 AP2/ERF gene families were found and classified into four… More >

Giovana Pinheiro Viana da Silva¹, Edilson Costa^1,*, Paulo Henrique Rosa Melo¹, Fernanda Pacheco de Almeida Prado Bortolheiro¹, Thaise Dantas², Flávio Ferreira da Silva Binotti¹, Carlos Eduardo da Silva Oliveira¹, Abimael Gomes da Silva¹

Phyton-International Journal of Experimental Botany, Vol.94, No.10, pp. 3109-3123, 2025, DOI:10.32604/phyton.2025.070221 - 29 October 2025

Abstract Hancornia speciosa ‘Gomes’, commonly known as mangabeira, is a fruit-bearing tree native to Brazil that plays a crucial role in sustaining its native biome, restoring degraded areas, and improving the socio-environmental conditions of these regions. The use of colored materials and bioinputs can help improve the quality of seedling production of Hancornia speciosa. This study aimed to evaluate the use of colored seedling tubes and a Chlorella vulgaris-based bioinput in developing Hancornia speciosa seedlings. The experiment was conducted at the Mato Grosso do Sul State University (UEMS), in Cassilândia, MS, using a completely randomized design in a 5 ×… More >