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    ARTICLE

    Preparation and Properties of Guiqi Polysaccharides/Chitosan/Alginate Composite Hydrogel Microspheres

    Xiaoliang Zhao1,#, Yuting Wang1,#, Xiuying Pu1, Jianzhong Ma1, Feifan Leng1, Yonggang Wang1, Yanling Wang1, Shuhong Yang1, Fen Ran2, Weijie Zhang1,*

    Journal of Renewable Materials, Vol.7, No.12, pp. 1321-1332, 2019, DOI:10.32604/jrm.2019.07757

    Abstract A series of the Guiqi polysaccharides/chitosan/alginate composite hydrogel microspheres (GPcM) with different particle sizes were prepared with Guiqi polysaccharides (GP), chitosan (CS) and sodium alginate (Alg). The optimum preparation process was also determined by single factor and orthogonal experiment analysis. The GPcM were characterized by fourier transform infrared spectroscopy (FT-IR), scanning electron microscope (SEM), drug loading efficiency test (LE), encapsulation efficiency test (EE) and in vitro release study. The results showed that the Guiqi polysaccharides chitosan hydrogel (GPCH) and sodium alginate hydrogel (SAH) formed a crossover system in GPcM. The GPcM have a uniform particle size ranging from 395.1μm to… More >

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