Victoire Vigneron^1,2,*, Eugénie Gosset Grainville¹

Psycho-Oncologie, Vol.18, No.1, pp. 43-48, 2024, DOI:10.32604/po.2023.043095

Abstract Cet article illustre la pratique clinique en psycho-oncologie, au sein d’un service d’onco-hématologie pédiatrique par de jeunes psychologues. Pour commencer, nous aborderons la place du psychologue dans un service somatique. La créativité dans le travail clinique et la modulation de temporalité médicale. Il s’agit ici de discuter la construction de l’identité professionnelle en lien avec la construction de l’alliance thérapeutique avec les patients. Spécifiquement nous aborderons le rapport à la créativité, nécessaire pour accompagner des enfants et adolescents dans leurs questionnements existentiels. Ce travail de créativité dans l’alliance thérapeutique, sera illustré à l’aide de deux cas cliniques particulièrement représentatifs du… More >

Wenyuan Chen¹, Tao Zhang², Yantao Yang^1,*

The International Conference on Computational & Experimental Engineering and Sciences, Vol.27, No.3, pp. 1-1, 2023, DOI:10.32604/icces.2023.09754

Abstract Based on the moving-least-squares immersed boundary method, we proposed a new technique to improve the calculation of the volume force representing the body boundary. For boundary with simple geometry, we theoretically analyze the error between the desired volume force at boundary and the actual force applied by the original method. The ratio between the two forces is very close to a constant and exhibits a very narrow distribution. A spatially uniform coefficient is then introduced to correct the force and can be fixed by the least-square method over all boundary markers. Such method is explicit and non-iterative, and is easy… More >

P. Sabitha^*, G. Meeragandhi

Intelligent Automation & Soft Computing, Vol.37, No.2, pp. 1983-2000, 2023, DOI:10.32604/iasc.2023.034402

Abstract Developing an automatic and credible diagnostic system to analyze the type, stage, and level of the liver cancer from Hematoxylin and Eosin (H&E) images is a very challenging and time-consuming endeavor, even for experienced pathologists, due to the non-uniform illumination and artifacts. Albeit several Machine Learning (ML) and Deep Learning (DL) approaches are employed to increase the performance of automatic liver cancer diagnostic systems, the classification accuracy of these systems still needs significant improvement to satisfy the real-time requirement of the diagnostic situations. In this work, we present a new Ensemble Classifier (hereafter called ECNet) to classify the H&E stained… More >

Yuan Hu¹, Xiaohui Yang², Jie Dong³, Peng Huang², Jinwen Luo², Guangxian Yang², James D. St. Louis⁴, Xicheng Deng^2,*

Congenital Heart Disease, Vol.17, No.6, pp. 687-695, 2022, DOI:10.32604/chd.2022.024333

Abstract Background: Interventricular septal hematoma is a rare complication after congenital cardiac repair. The management varies according to the literature. We present our experience with this rare complication. Methods: Echocardiography database were reviewed with the term ‘‘hematoma’’ or “hypoechoic mass” for patients who underwent congenital heart surgery from January 2018 to December 2021 at our institution to identify potential interventricular septal hematoma cases. Relevant data of the patients identified were collected. Focus was put on the presentation, management, outcomes according to patent medical charts and serial echocardiographic report data. Results: In total, there were 5 patients included. The mean age and… More > Graphic Abstract

Giuseppe Emmanuele Umana^1,*, Gianluca Ferini², Antonio Crea¹, Bipin Chaurasia³, Vishal Chavda⁴, Leonardo Corbino¹, Daniele Franceschini¹, Maria Grazia Tranchina⁵, Marco Fricia¹, Francesca Graziano⁶, Giovanni Federico Nicoletti⁶, Salvatore Cicero¹, Gianluca Scalia⁶

Oncologie, Vol.24, No.2, pp. 341-348, 2022, DOI:10.32604/oncologie.2022.021347

Abstract Concomitant acute epidural hematoma (EDH) and subdural hematoma (SDH) is a rare finding, and its bilateral onset has not yet been reported in literature. We present the first report of a patient affected by post-traumatic concomitant EDH and SDH, with the contralateral, delayed onset of another, associated with meningioma previously treated with gamma knife. A 60-year-old female patient with a history of simple focal seizures with motor symptoms and well-controlled by drugs since childhood, arterial hypertension, and incidental diagnosis of multiple meningiomas was referred to our department after falling down the stairs. Initially, the patient was prescribed gamma knife treatment… More >

LIANGYING ZHANG¹, SHAOTING ZHANG¹, ZHAOYANG FAN¹, ZONGYING JIANG^1,2, ANBU LIU¹, SHUJING LI^1,2, JIANMIN SUN^1,*

BIOCELL, Vol.46, No.9, pp. 2081-2087, 2022, DOI:10.32604/biocell.2022.020109

Abstract PI3 kinases are important for KIT signaling and KIT mutants mediated cell transformation. In order to know the difference of PI3 kinase isoforms p110α and p110δ in the signaling of wild-type KIT and the often occurred KIT mutation D816V in hematopoietic malignancy mastocytosis, the predominant PI3 kinase isoform p110δ in hematopoietic tissues was knocked out in hematopoietic cells. We found that loss of p110δ expression dramatically inhibits PI3 kinase activation mediated by both wild-type KIT and KIT/D816V. By over expression of p110α in p110δ knock out cells, wild-type KIT mediated PI3 kinase activation was not changed while over expression of… More >

XIANLIANG HOU^1,2,3,#, DONGE TANG^1,#, FENGPING ZHENG^1,#, MINGLIN OU³, YONG XU¹, HUIXUAN XU¹, XIAOPING HONG⁴, XINZHOU ZHANG¹, WEIER DAI⁵, DONGZHOU LIU^4,*, YONG DAI^1,*

BIOCELL, Vol.44, No.4, pp. 559-582, 2020, DOI:10.32604/biocell.2020.011022

Abstract Systemic lupus erythematosus (SLE) is a systemic autoimmune disease characterized by abnormal cellular and humoral immune responses and excessive autoantibody production. The precise pathologic mechanism of SLE remains elusive. The advent of single-cell RNA sequencing (scRNA-seq) enables unbiased analysis of the molecular differences of cell populations at the single-cell level. We used scRNA-seq to profile the transcriptomes of peripheral blood mononuclear cells from an SLE patient compared with a healthy control (HC). A total of 16,021 cells were analyzed and partitioned into 12 distinct clusters. The marker genes of each cluster and the four major immune cell types (B cells,… More >

YAQUN HONG^1,2, BO WAN³, XIAOFAN LI^1,4,*

BIOCELL, Vol.44, No.2, pp. 237-246, 2020, DOI:10.32604/biocell.2020.08887

Abstract Most studies focus on the adaptive immune cells in the GVHD pathogenesis, while little is known about innate immune cells in GVHD occurrence and development, especially macrophages. Meanwhile, a higher incidence of graft versus host disease (GVHD) is also found in the elderly patients. Though advances have been made in the modification of macrophages influenced by the inflamm-ageing, there is still no review on the role of macrophages in GVHD and the association between GVHD and the altered macrophages by inflamm-ageing. In this review, we focus on the potential age-related modifications of macrophage in GVHD, which contributes to the change… More >

Patrick D. Evers^1,*, Tarek Alsaied^1,2,*, Jeffrey B. Anderson¹, James F. Cnota¹, Allison A. Divanovic¹

Congenital Heart Disease, Vol.14, No.2, pp. 221-229, 2019, DOI:10.1111/chd.12713

Abstract Objective: Maternal anti-Ro/SSA and anti-La/SSB antibodies can lead to fetal complete heart block (CHB). Current guidelines recommend weekly echocardiographic screening between 16 and 28 weeks gestation. Given the cost of screening and the rarity of conduction abnormalities in fetuses of mothers with low anti-Ro levels (<50 U/mL), we sought to identify a strategy that optimizes resource utilization.
Design: Decision analysis cost-utility modeling was performed for three screening paradigms: “standard screening” (SS) in which mid-gestation mothers are screened weekly, “limited screening” (LS) in which fetal echocardiograms are avoided unless the fetus develops bradycardia, and “targeted screening by maternal antibody level” (TS)… More >

R. Canabarro^1,2, H. Sporleder², T. Gomes^3,4, G. Zanatta^3,5, L. Scribel^3,6, F. Freitas⁷, J. Neumann², P. Pranke^1,3

BIOCELL, Vol.31, No.3, pp. 397-403, 2007, DOI:10.32604/biocell.2007.31.397

Abstract The use of umbilical cord blood stem cells is an efficient alternative for the transplantation of hematopoietic progenitor cells. A number of factors can influence the volume and amount of CD34⁺ cells, which are considered as immature and capable of proliferation. Quantification of CD34⁺ cells, evaluation of CD38 and c-kit molecules on these cells, as well as correlations of such factors as maternal age, gestational age, newborn sex and weight, umbilical cord length, placental weight with increased volume and concentration of immature cells, among others, were performed in 70 blood samples from term newborns. The mean volume of umbilical cord… More >