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    ARTICLE

    Computational Modeling of Human Bicuspid Pulmonary Valve Dynamic Deformation in Patients with Tetralogy of Fallot

    Caili Li1, §, Christopher Baird2, Jing Yao3, Chun Yang4, Liang Wang5, Han Yu5, Tal Geva6, Dalin Tang5*, 7, §

    CMES-Computer Modeling in Engineering & Sciences, Vol.119, No.1, pp. 227-244, 2019, DOI:10.32604/cmes.2019.06036

    Abstract Pulmonary valve stenosis (PVS) is one common right ventricular outflow tract obstruction problem in patients with tetralogy of Fallot (TOF). Congenital bicuspid pulmonary valve (BPV) is a condition of valvular stenosis, and the occurrence of congenital BPV is often associated with TOF. Dynamic computational models of normal pulmonary root (PR) with tri-leaflet and PR with BPV in patients with TOF were developed to investigate the effect of geometric structure of BPV on valve stress and strain distributions. The pulmonary root geometry included valvular leaflets, sinuses, interleaflet triangles and annulus. Mechanical properties of pulmonary valve leaflet were obtained from biaxial testing… More >

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