Zongqiang GAO1, Xiong GUO2, Junchang CHEN1, Chen DUAN2
BIOCELL, Vol.43, No.2, pp. 99-102, 2019, DOI:10.32604/biocell.2019.06520
Abstract This study aimed to investigate the effect of hyaluronic acid (HA) on the expression of heat shock protein
70 (HSP70) in chondrocytes isolated from patients with osteoarthritis (OA) and Kashin-Beck disease (KBD). The
chondrocytes were collected from OA and KBD patients, and chondrocytes isolated from patients of accident injuries
were used as the control. The chondrocytes were treated with HA at different doses. HSP70 expression in chondrocytes
at both mRNA and protein levels was tested by PCR and Western blot analysis. Compared with control, both mRNA
and protein levels of HSP70 were higher in chondrocytes from KBD and OA. However,… More >
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