JOÃO OLIVEIRA PEREIRA1,2,*, JOÃO GAMA3, DIANA FERREIRA2,4, ARSÉNIO SANTOS2,4
Oncology Research, Vol.29, No.2, pp. 81-85, 2021, DOI:10.32604/or.2022.023450
Abstract Hypercalcaemia and leukocytosis are two paraneoplastic conditions associated with poor prognosis.
Adenosquamous carcinoma is a rare and aggressive histological subtype of lung cancer consisting of adenocarcinoma
and squamous cell components. We report the case of a 57-year-old male smoker who was admitted to the Emergency
Room with skull and neck tumefactions, confusion and deteriorated general condition. The complementary study in the
ER revealed severe hypercalcaemia (19.8 mg/dL), leukocytosis (18.7 × 109
/L) and extensive osteolytic lesions of the skull
on cranioencephalic computer tomography (CT). The patient was stabilized and admitted. Thoracoabdominopelvic CT
showed lung parenchyma consolidation with necrotic areas, supra… More >