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    ARTICLE

    Changes in neuropeptides related to food intake in the rat arcuate nucleus after chronic immobilization stress and the effect of comfortable music exposure

    HAO WANG1,2,#, FANG FANG1,#, CHAOYI FANG1, RUNSHENG ZHAO1,*, SHAOXIAN WANG1,*

    BIOCELL, Vol.44, No.3, pp. 421-429, 2020, DOI:10.32604/biocell.2020.010257

    Abstract Stress is an inevitable interference factor that seriously affects health. Listening to music is an economical, noninvasive, and highly accepted tool for easing stress. However, physiological studies investigating the ability of music to reduce stress in daily life are limited. We established rat models of chronic immobilization stress (CIS) to observe changes in the hypothalamic arcuate nucleus (ARC) neurons involved in the regulation of food intake and the effect of comfortable classical music exposure. Twenty-one days of stress resulted in decreased food intake and delayed body weight gain; up-regulation of leptin receptor (Ob-R), cocaine- and amphetamine-regulated transcript (CART), proopiomelanocortin (POMC),… More >

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