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    ARTICLE

    Analysis of the personalized treatment and the relevant prognostic factors in children with medulloblastoma

    LIHUA CHEN1,2,#, HONGTIAN ZHANG1,2,#, YONG XIA1,2, KAI SUN1, WENJIN CHEN1, RUXIANG XU1,2,*

    BIOCELL, Vol.47, No.5, pp. 1065-1073, 2023, DOI:10.32604/biocell.2023.025924

    Abstract Purpose: The present study summarized cases of children (n = 32) with medulloblastoma (MB) who were treated using stratified therapy based on risk grading and also discussed the factors affecting prognosis. Methods: According to the risk stratification criteria, the cases were divided into the following four risk groups: low, standard, high, and very high. The 5-year overall survival (OS) and progression-free survival (PFS) rates were summarized. Further, the effects on the prognosis of tumor size, tumor stage, degree of resection, treatment mode, metastatic recurrence, molecular typing, and risk stratification were analyzed. Results: In the present study, following surgery, 3 cases… More >

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