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    Partial Contact Indentation Tonometry for Measurement of Corneal Properties-Independent Intraocular Pressure

    Match W L Ko, Leo K K Leung, David C C Lam∗,†

    Molecular & Cellular Biomechanics, Vol.9, No.4, pp. 251-268, 2012, DOI:10.3970/mcb.2012.009.251

    Abstract Inter-individual differences in corneal properties are ignored in existing methods for measuring intraocular pressure IOP, a primary parameter used in screening and monitoring of glaucoma. The differences in the corneal stiffness between individuals can be more than double and this difference would lead to IOP measurement errors up to 10 mmHg. In this study, an instrumented partial-contact indentation measurement and analysis method that can account for inter-individual corneal difference in stiffness is developed. The method was tested on 12 porcine eyes ex vivo and 7 rabbit eyes in vivo, and the results were compared to the controlled IOPs to determine… More >

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