FEI TIAN*, GANG LIU, LINLIN FAN, ZHONGYUN CHEN, YAN LIANG,
BIOCELL, Vol.45, No.1, pp. 49-56, 2021, DOI:10.32604/biocell.2021.013794
Abstract Cerebral ischemia is due to the formation of blood clots or embolisms in the brain arteries, which leads to local
brain tissue necrosis and neural cell apoptosis. Recent studies have shown that microRNA (miRNA) plays an important
regulatory role in the pathological process of ischemic injury. The aim of this study is to investigate the role and the
mechanism of miR-21-3p and drosophila mothers against decapentaplegic 2 (SMAD2) in cerebral ischemic
reperfusion injured (CIRI) neural cells. The CIRI model was established by oxygen-glucose deprivation and recovery
process for N2a cells. The cell viability and the apoptotic was evaluated by MTT… More >
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