JIATENG ZHONG1,2, JINGYU GUO1, XINYU ZHANG1, SHUANG FENG1, WENYU DI2, YANLING WANG3,*, HUIFANG ZHU1,*
Oncology Research, Vol.30, No.5, pp. 231-242, 2022, DOI:10.32604/or.2022.027900
Abstract Lipid is a key component of plasma membrane, which plays an important role in the regulation of various cell
biological behaviors, including cell proliferation, growth, differentiation and intracellular signal transduction. Studies
have shown that abnormal lipid metabolism is involved in many malignant processes, including colorectal cancer
(CRC). Lipid metabolism in CRC cells can be regulated not only by intracellular signals, but also by various
components in the tumor microenvironment, including various cells, cytokines, DNA, RNA, and nutrients including
lipids. In contrast, abnormal lipid metabolism provides energy and nutrition support for abnormal malignant growth
and distal metastasis of CRC cells. In… More >
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