Purushottam Sharma¹, Mohammed Alshehri^2,*, Richa Sharma¹, Osama Alfarraj³

CMC-Computers, Materials & Continua, Vol.66, No.1, pp. 885-901, 2021, DOI:10.32604/cmc.2020.012251

Abstract Low back pain (LBP) is a morbid condition that has afflicted several citizens in Europe. It has negatively impacted the European economy due to several man-days lost, with bed rest and forced inactivity being the usual LBP care and management steps. Direct models, which incorporate various regression analyses, have been executed for the investigation of this premise due to the simplicity of translation. However, such straight models fail to completely consider the impact of association brought about by a mix of nonlinear connections and autonomous factors.In this paper, we discuss a system that aids decision-making regarding the best-suited support system… More >

Yongren Wu^∗, Sarah Cisewski^∗, Barton L. Sachs^†, Hai Yao^∗,†,‡

Molecular & Cellular Biomechanics, Vol.10, No.2, pp. 159-182, 2013, DOI:10.3970/mcb.2013.010.159

Abstract This study examines the effects of cartilage endplate (CEP) calcification and the injection of intervertebral disc (IVD) cells on the nutrition distributions inside the human IVD under physiological loading conditions using multiphasic finite element modeling. The human disc was modeled as an inhomogeneous mixture consisting of a charged elastic solid, water, ions (Na⁺ and Cl⁻), and nutrient solute(oxygen,glucose and lactate) phases. The effect of the endplate calcification was simulated by a reduction of the tissue porosity (i.e., water volume faction) from 0.60 to 0.48. The effect of cell injection was simulated by increasing the cell density in the nucleus pulposus… More >