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  • Open Access

    ARTICLE

    Numerical Evaluation of Residual Water Content after Freezing during the Lyophilization of Platelets

    Shaozhi Zhang, Ruoyi Xie, Mengjie Xu, Guangming Chen*

    FDMP-Fluid Dynamics & Materials Processing, Vol.16, No.6, pp. 1177-1189, 2020, DOI:10.32604/fdmp.2020.010352

    Abstract Pre-freezing is an important stage in freeze-drying processes. For the lyophilization of a cell, freezing not only plays a role for primary dehydration, but it also determines the amount of residual (intracellular or extracellular) water, which in turn can influence the solution properties and the choice of operation parameters. The freezing of human platelets in lyoprotectant solution is theoretically investigated here. A two-parameter model and an Arrhenius expression are used to describe cell membrane permeability and its temperature dependency. It is assumed that the intracellular solution is composed of four components: sodium chloride, trehalose, serum protein and water, while the… More >

  • Open Access

    ARTICLE

    Structure-Thermal Conductivity Tentative Correlation for Hybrid Aerogels Based on Nanofibrillated Cellulose-Mesoporous Silica Nanocomposite

    Dounia Bendahou1,2, Abdelkader Bendahou1, Bastien Seantier1, Bénédicte Lebeau3, Yves Grohens1,*, Hamid Kaddami2,*

    Journal of Renewable Materials, Vol.6, No.3, pp. 299-313, 2018, DOI:10.7569/JRM.2017.634185

    Abstract Hybrid aerogels have been prepared by freeze-drying technique after mixing water dispersions of cellulose microfibers or cellulose nanofibers and silica (SiO2) of type SBA-15 (2D-hexagonal). The prepared composites were characterized by different analysis techniques such as SEM, hot-filament, DMA, etc. These composites are compared to those previously prepared using nanozeolites (NZs) as mineral charge. The morphology studied by SEM indicated that both systems have different structures, i.e., individual fibers for cellulose microfibers WP-based aerogels and films for nanofibrillated cellulose NFC-based ones.... These differences seem to be driven by the charge of the particles, their aspect ratio and concentrations. These hybrid… More >

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