Si Qin, Shu Tang, Lijiao Xie, Jianbo Zhu, Jianguo Sun^*

Oncology Research, Vol.33, No.12, pp. 4145-4154, 2025, DOI:10.32604/or.2025.068300 - 27 November 2025

Abstract Background: Primary pulmonary lymphoepithelioma-like carcinoma (PPLELC) is a rare subtype of primary non-small cell lung cancer (NSCLC), with no established treatment guidelines. We present a case of a young female with PPLELC who achieved a pathological complete response (pCR) in both primary and metastatic lesions after receiving combined immunotherapy and radiotherapy. Case description: We present a 33-year-old female patient with stage IVa (cT2bN0M1b) PPLELC. As a first-line treatment, the patient received seven cycles of nab-paclitaxel combined with toripalimab (a PD-1 inhibitor) and achieved stable disease. This was followed by toripalimab maintenance therapy for nearly 30 months.… More >

Dong Liu¹, Runze Zhang¹, Anjie Hu¹, Na Liu¹, Liu Tang^2,3,*, Xiaozhou Wu⁴, Jun Wang^2,5

FDMP-Fluid Dynamics & Materials Processing, Vol.21, No.10, pp. 2579-2612, 2025, DOI:10.32604/fdmp.2025.070407 - 30 October 2025

Abstract This study compares two end-cooling systems, convective–radiant combined cooling (FR+FC) and fan coil convection (FC), through continuous experimental investigations, focusing on the impact of window-to-wall ratio (WWR) on indoor thermal comfort, temperature distribution, humidity, and energy consumption. Results show that increasing WWR amplifies indoor temperature fluctuations. While the overall predicted mean vote (PMV) remains within the Level-II comfort range (−1.0 to +1.0), the FC system exhibits pronounced local PMV gradients near west-facing windows, especially at 80% WWR, where transient PMV reaches 1.26 close to the window, 0.89 higher than at the room center. In contrast, More >

Iqbal Singh^1,*, Himanshu Agrawal², Vidhi Maurya², Sanjay Gupta², Alpana Raizada³

Canadian Journal of Urology, Vol.32, No.4, pp. 299-308, 2025, DOI:10.32604/cju.2025.064827 - 29 August 2025

Abstract Objectives: Benign prostatic hyperplasia (BPH) is a common benign tumor in men, with an age-related prevalence of multifactorial etiology. The present study aimed to accurately assess and predict the effect of co-existing metabolic syndrome (MtS) upon treatment outcomes of combination medical therapy in select patients of lower urinary tract symptoms (LUTS) due to BPH. Methods: After obtaining informed consent from the patients, 70 eligible patients with LUTS due to BPH with and without MtS were enrolled in this study from September 2022 to January 2024 from the outpatient clinic at the University College of Medical… More >

Alya Penta Agharid¹, Indra Permana², Linlan Chang¹, Yi-Han Luo², Fujen Wang^2,*

Energy Engineering, Vol.122, No.9, pp. 3839-3866, 2025, DOI:10.32604/ee.2025.068586 - 26 August 2025

Abstract Air conditioning (AC) is essential for maintaining indoor comfort during Taiwan’s hot and humid summers but significantly contributes to increased energy consumption. This study evaluates the effects of AC duty-cycling strategies on energy performance, thermal comfort, and operational costs in office environments. Duty-cycling was implemented using a building energy management system (BEMS), which remotely controlled the ON/OFF cycles of AC units. Five duty-cycling modes were tested, with some modes incorporating air circulation during OFF periods. Field measurements of energy consumption, temperature, humidity, and air velocity were conducted and integrated with thermal comfort analysis tools to… More >

Wei Shi^1,2, Shusheng Xiong^1,2,3,*, Wei Li^2,3, Kai Meng⁴, Qingsheng Liu⁴

Energy Engineering, Vol.122, No.9, pp. 3507-3523, 2025, DOI:10.32604/ee.2025.065579 - 26 August 2025

Abstract In the realm of all-electric aircraft research, the integration of cathode-open proton exchange membrane fuel cells (PEMFC) with lithium batteries as a hybrid power source for small to medium-sized unmanned aerial vehicles (UAVs) has garnered significant attention. The PEMFC, serving as the primary energy supply, markedly extends the UAV’s operational endurance. However, due to payload limitations and spatial constraints in the airframe layout of UAVs, the stack requires customized adaptation. Moreover, the implementation of auxiliary systems to facilitate cold starts of the PEMFC under low-temperature conditions is not feasible. Relying solely on thermal insulation measures… More >

Yanjie Liu, Ximin Cao^*, Yanchi Zhang

Energy Engineering, Vol.122, No.8, pp. 3377-3398, 2025, DOI:10.32604/ee.2025.066577 - 24 July 2025

Abstract Under the “dual carbon” goals, this paper constructs an optimization model of the comprehensive energy system in the park. A stepwise carbon excess rate mechanism and an electric vehicle coupling strategy are proposed: A carbon quota trading system is established based on the baseline method, and the stepwise function is adopted to quantify the cost of excess carbon emissions; Introduce the price demand response and the two-way interaction mechanism of electric Vehicle vehicle-to-grid (V2G) to enhance the flexible regulation ability. Aiming at the uncertainty of wind and solar output, a typical scene set is generated… More >

Li Niu¹, Yang Wang^1,*, Nan Lin², Yaoying Yue¹, Wenbin Fu¹, Elzat Tuhanjiang¹

FDMP-Fluid Dynamics & Materials Processing, Vol.21, No.6, pp. 1473-1487, 2025, DOI:10.32604/fdmp.2025.062623 - 30 June 2025

Abstract With the widespread use of polyethylene (PE) materials in gas pipelines, the problem related to the aging of these pipes has attracted increasing attention. Especially under complex environmental conditions involving temperature, humidity, and pressure changes, PE pipes are prone to oxidative degradation, which adversely affects their performance and service life. This study investigates the aging behavior of PE pipes used for gas transport under the combined effects of temperature (ranging from 80°C to 110°C) and pressure (0, 0.1, 0.2, and 0.3 MPa). By assessing the characteristics and thermal stability of the aged pipes, relevant efforts… More >

Hongen Li, Hongjuan Ren^*, Cong Li, Yecui Yan

Frontiers in Heat and Mass Transfer, Vol.23, No.3, pp. 921-941, 2025, DOI:10.32604/fhmt.2025.066512 - 30 June 2025

Abstract The flow field architecture of the proton exchange membrane fuel cell (PEMFC) cathode critically determines its performance. To enhance PEMFC operation through structural optimization, trapezoidal obstacles were implemented in the cathode flow channels. The height dependence of these obstacles was systematically investigated, revealing that a 0.7 mm obstacle height enhanced mass transfer from channels to the gas diffusion layer (GDL) compared to conventional triple-serpentine designs. This configuration achieved a 12.08% increase in limiting current density alongside improved water management. Subsequent studies on obstacle distribution density identified 75% density as optimal, delivering maximum net power density More >

K. Sinivasan¹, N. Vishnu Ganesh^1,*, G. Hirankumar², M. Al-Mdallal Qasem^3,*

FDMP-Fluid Dynamics & Materials Processing, Vol.21, No.5, pp. 1029-1049, 2025, DOI:10.32604/fdmp.2025.064503 - 30 May 2025

Abstract In this study, an analytical investigation is carried out to assess the impact of magnetic field-dependent (MFD) viscosity on the momentum and heat transfers inside the boundary layer of a Jeffrey fluid flowing over a horizontally elongating sheet, while taking into account the effects of ohmic dissipation. By applying similarity transformations, the original nonlinear governing equations with partial derivatives are transformed into ordinary differential equations. Analytical expressions for the momentum and energy equations are derived, incorporating the influence of MFD viscosity on the Jeffrey fluid. Then the impact of different parameters is assessed, including magnetic More >

Linlan Chang¹, Win-Jet Luo^1,2, Indra Permana², Bowo Yuli Prasetyo³, Alya Penta Agharid¹, Fujen Wang^2,*

Energy Engineering, Vol.122, No.5, pp. 1771-1787, 2025, DOI:10.32604/ee.2025.062209 - 25 April 2025

Abstract Heating, Ventilation, and Air Conditioning (HVAC) systems are critical for maintaining thermal comfort in office environments which also crucial for occupant well-being and productivity. This study investigates the impact of integrating ceiling fans with higher air conditioning setpoints on thermal comfort and energy efficiency in office environments. Field measurements and questionnaire surveys were conducted to evaluate thermal comfort and energy-saving potential under varying conditions. Results show that increasing the AC setpoint from 25°C to 27°C, combined with ceiling fan operation, reduced power consumption by 10%, achieving significant energy savings. Survey data confirmed that 85% of… More >