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    ARTICLE

    Relationship of multidrug-resistant gene and extended-spectrum carbapenem-resistance in Staphylococcus aureus

    Yuan LI1, Yonghyun LEE2, Yielhea SEO3, Youjin HWANG1, 2, *

    BIOCELL, Vol.43, No.4, pp. 263-269, 2019, DOI:10.32604/biocell.2019.07664

    Abstract The aim of this study was to determine the relationship between phenotypic antimicrobial susceptibility patterns and extended-spectrum, carbapenem-resistance genes. A total of 109 clinical Staphilococcus aureus strains were subjected to 19 antimicrobial susceptibility tests. Resistance to methicillin (mecA), penicillin (blaTEM), and tetracycline (tetM) was detected. We compared the presence of the blaTEM genes with extended-spectrum, carbapenem-related genes and identified the types of SCCmec genes. Of 109 clinical S. aureus strains, 62 (56.88%) had methicillin resistance and 60 strains carried mecA. The prevalence of blaTEM and tetM genes was 81.65% and 37.61%, respectively. The most predominant SCCmec type was SCCmec type… More >

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