Shaoxiong Yang1, Xiaobo Gong1,*, Yingxin Qi2, Zonglai Jiang2
Molecular & Cellular Biomechanics, Vol.16, Suppl.1, pp. 9-10, 2019, DOI:10.32604/mcb.2019.05701
Abstract Blood vessels interact with their mechanical environments in a comprehensive way. Local mechanical stimuli outside the biological range play important roles in various human cardiovascular diseases. Although many mechanobiological studies of endothelial cells (ECs) and vascular smooth muscle cells (VSMCs) in vitro have been reported in mimicking cellular dysfunctions, their quantitative correlations to the in vivo vascular conditions remain unclear. In order to interpret the stress-modulated dysfunctions of vascular cells and explore the key mechanical factors in vascular diseases, it is important to investigate the mechanical environments of vessel walls in vivo under various physiological conditions. Based on nonlinear continuum… More >
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