D.E. Ingber1
Molecular & Cellular Biomechanics, Vol.1, No.1, pp. 53-68, 2004, DOI:10.3970/mcb.2004.001.053
Abstract This article is a summary of a lecture presented at a symposium on "Mechanics and Chemistry of Biosystems'' in honor of Professor Y.C. Fung that convened at the University of California, Irvine in February 2004. The article reviews work from our laboratory that focuses on the mechanism by which mechanical and chemical signals interplay to control how individual cells decide whether to grow, differentiate, move, or die, and thereby promote pattern formation during tissue morphogenesis. Pursuit of this challenge has required development and application of new microtechnologies, theoretical formulations, computational models and bioinformatics tools. These approaches have been used to… More >
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