LAKSHANA SADU#, R.HARI KRISHNAN#, R.L. AKSHAYA, I. SARANYA, UDIPT RANJAN DAS, SNEHA SATISHKUMAR, N. SELVAMURUGAN*
BIOCELL, Vol.47, No.4, pp. 751-760, 2023, DOI:10.32604/biocell.2023.026911
Abstract MicroRNAs (miRNAs) are small non-coding RNAs (ncRNAs) that regulate the expression of their target mRNAs
post-transcriptionally. Since their discovery, thousands of highly conserved miRNAs have been identified and investigated
for their role in human health and diseases. MiR-214 has been increasingly reported to have an association with the
regulation of bone metabolism. Reports suggested that miR-214 controls the critical aspects of osteoblasts (bone-forming
cells), including their differentiation, proliferation, viability, and migration. Studies have also reported the functional
significance of miR-214 in bone diseases and suggested its candidature as a diagnostic and therapeutic target. Further,
targeting miR-214 by other ncRNAs, such… More >
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