TIANQI WANG, WANXI YANG*
BIOCELL, Vol.44, No.4, pp. 469-478, 2020, DOI:10.32604/biocell.2020.014708
Abstract Mitochondria are important in eukaryotic cells due to their functions in energy production and regulation over
other cellular activities. Oocytes are produced by a long and precisely controlled process, the dysfunction of which leads to
impaired female fertility. As oocytes mature, mitochondria are constantly under the regulation of nuclear genes, the
process of which can be modulated by extracellular signals. Understanding how nuclear genes regulate mitochondrial
functions is important for studying animal reproduction and human fertility. As more and more genes regulating
mitochondrial functions in oocytes are being revealed, new approaches for improving female fertility in both human
and animals… More >
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