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    ARTICLE

    Decreased CD10-positive granulocytes for the differential diagnosis of myelodysplastic syndrome

    JIYU WANG#, HUIPING WANG#, YING PAN, QIANSHAN TAO, ZHIMIN ZHAI*

    BIOCELL, Vol.44, No.4, pp. 607-611, 2020, DOI:10.32604/biocell.2020.010947

    Abstract Myelodysplastic syndromes (MDS) are highly heterogeneous myeloid neoplasms, and a large number of patients are difficult to diagnose and classify by blood and bone marrow examination. As a surface marker of granulocyte, studies have shown CD10 can be used to define the degree of granulocyte maturation in MDS patients. However, whether it can be used for differential diagnosis of MDS and other hematological diseases remains inconclusive. To explore the value of CD10 for differential diagnosis of MDS, 60 newly diagnosed MDS, 20 aplastic anemia (AA) patients, and 35 iron-deficient anemia (IDA) patients were selected for this study. Bone marrow (BM)… More >

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