Ozlem OZ*
Oncologie, Vol.22, No.3, pp. 155-160, 2020, DOI:10.32604/oncologie.2020.014087
Abstract Neurofibromatosis type 1 is an autosomal dominant disorder which is
characterized by multiple café-au-lait spots in the body, intertriginous freckles,
Lisch nodules, neurofibroma, optic glioma and bone dysplasia. One of the
clinical characteristics of Neurofibromatosis type 1 is the risk of benign and
malignant tumor development. Optic gliomas, a type of astrocytoma, are the
most common central nervous system complication in children with
Neurofibromatosis type 1 and are seen in 10–15% of cases. In this case report, a
patient with an optic glioma and a mutation that was not previously identified in
the NF1 gene is presented in the light… More >
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