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  • Open Access

    REVIEW

    Recent updates on nano-phyto-formulations based therapeutic intervention for cancer treatment

    ABHISHEK WAHI1, MAMTA BISHNOI2, NEHA RAINA1, MEGHNA AMRITA SINGH1, PIYUSH VERMA1, PIYUSH KUMAR GUPTA3,4, GINPREET KAUR5, HARDEEP SINGH TULI6,*, MADHU GUPTA1,*

    Oncology Research, Vol.32, No.1, pp. 19-47, 2024, DOI:10.32604/or.2023.042228

    Abstract Cancer is a leading cause of death globally, with limited treatment options and several limitations. Chemotherapeutic agents often result in toxicity which long-term conventional treatment. Phytochemicals are natural constituents that are more effective in treating various diseases with less toxicity than the chemotherapeutic agents providing alternative therapeutic approaches to minimize the resistance. These phytoconstituents act in several ways and deliver optimum effectiveness against cancer. Nevertheless, the effectiveness of phyto-formulations in the management of cancers may be constrained due to challenges related to inadequate solubility, bioavailability, and stability. Nanotechnology presents a promising avenue for transforming current cancer treatment methods through the… More > Graphic Abstract

    Recent updates on nano-phyto-formulations based therapeutic intervention for cancer treatment

  • Open Access

    ARTICLE

    Insecticidal Activity and Physicochemical Characterization of Nanoparticles from Foliar Extract of Capsicum chinense

    Arnoldo E. Alfaro-Corres1, Daniel González-Mendoza2, Esaú Ruiz-Sánchez1,*, Carlos Ail-Catzin2, Benjamín Valdez-Salas3, Federico Gutiérrez-Miceli4, Arturo Reyes-Ramírez1, Jacques Fils Pierre1

    Journal of Renewable Materials, Vol.11, No.11, pp. 3933-3943, 2023, DOI:10.32604/jrm.2023.031129

    Abstract This work was carried out to evaluate the insecticidal effect of mono, bi and trimetallic nanoparticles (NPs) from leaf extract of habanero pepper (Capsicum chinense Jacq.) on the red flour beetle (Tribolium castaneum herbst.) and cotton mealybug (Phenacoccus solenopsis Tinsley). The results showed that Cu NPs, Cu/Mn NPs and Zn/Cu NPs had high insecticidal effect against T. castaneum (63%–80% mortality after 96 h). The Cu NPs and Zn/Cu NPs showed also insecticidal effect against P. solenopsis, but to a lesser extent (20%–28% after 96 h). With regards to the physicochemical characterization, Cu NPs had a zeta potential of 21.1 mV,… More > Graphic Abstract

    Insecticidal Activity and Physicochemical Characterization of Nanoparticles from Foliar Extract of <i>Capsicum chinense</i>

  • Open Access

    ARTICLE

    Assessment of Nanoparticle-Enriched Solvents for Oil Recovery Enhancement

    Muayad M. Hasan1,*, Firas K. Al-Zuhairi2, Anfal H. Sadeq1, Rana A. Azeez1

    FDMP-Fluid Dynamics & Materials Processing, Vol.19, No.11, pp. 2827-2835, 2023, DOI:10.32604/fdmp.2023.027746

    Abstract Solvents are generally used to reduce the viscosity of heavy crude oil and ultimately enhance oil recovery. Recently, a new method has been introduced where nanoparticles (NPs) are exploited to induce enhanced oil recovery owing to their ability to improve the mobility ratio, dampen the interfacial tension, and alter rock wettability. This study investigated the integration of nano-alumina (Al2O3) NPs with an n-hexane solvent. In particular, a Brookfield viscometer has been used to measure the crude oil viscosity and it has been found that NPs can effectively lead to a significant decrease in the overall oil viscosity (70 cp using… More >

  • Open Access

    ARTICLE

    Impact of ZnSO and ZnO Nanoparticles on Seed Germination and Seedling Growth of Lettuce

    Adalberto Benavides-Mendoza1, Rebeca Betancourt-Galindo2, Nazario Francisco-Francisco3,*

    Phyton-International Journal of Experimental Botany, Vol.92, No.6, pp. 1831-1840, 2023, DOI:10.32604/phyton.2023.028085

    Abstract

    Micronutrient nanoparticles (NPs) are currently an option for chemical fertilization and biostimulation in crops. However, there is little information on the phytotoxic or biostimulatory effects of NPs at low concentrations of some elements, such as Zn. In this study, the effect of low concentrations of Zn oxide (ZnO) NPs on germination, growth variables, and nutritional attributes of lettuce (Lactuca sativa L.) was evaluated in comparison to Zn sulfate. Romaine lettuce seeds were treated with ZnSO4-- × 7H2O and ZnO NPs at Zn molar concentrations of 1 × 10−3, 5 × 10−3, 1 × 10−4, 5 × 10−4, 1… More >

  • Open Access

    REVIEW

    The Interface of Cancer, Their Microenvironment and Nanotechnology

    Natalia Roque1,#, Diana Matias2,#, Joana Balça-Silva3, Valéria Pereira Ferrer4, Luciana Santos Pessoa1, Tania Cristina Leite de Sampaio e Spohr1,5,*

    Oncologie, Vol.24, No.3, pp. 371-411, 2022, DOI:10.32604/oncologie.2022.024035

    Abstract Cancer is one of the deadliest diseases with a cure far from being found. Despite the extraordinary advances in the therapy approaches, only a few patients respond to treatments. The tumor microenvironment (TME) plays a crucial role in cancer progression by contributing to the chemoresistance. Thus, emerging efforts are being made in nanotechnology research focusing on nanoparticles’ potential role and their application in immune system modulation. Moreover, the omics have contributed to bioengineering and nanotechnology development by elucidating the mechanisms of cancer and specific biomarkers that could be used as new therapeutic targets. Furthermore, the non-coding microRNA as a target… More >

  • Open Access

    ARTICLE

    Application of two forms of silicon and their impact on the postharvest and the content of bioactive compounds in cucumber (Cucumis sativus L.) fruits

    YOLANDA GONZÁLEZ-GARCÍA1, VALERIA FLORES-ROBLES2, GREGORIO CADENAS-PLIEGO3, ADALBERTO BENAVIDES-MENDOZA4, MARCELINO CABRERA DE LA FUENTE4, ALBERTO SANDOVAL-RANGEL4, ANTONIO JUÁREZ-MALDONADO1,*

    BIOCELL, Vol.46, No.11, pp. 2497-2506, 2022, DOI:10.32604/biocell.2022.021861

    Abstract The metabolic activity of the fruits continues even after harvest, which results in the loss of bioactive compounds, a decrease in the quality of the fruits, softening and browning, among other negative effects. The use of certain elements such as silicon can improve postharvest quality, since it is involved in the metabolic, physiological and structural activity of plants, moreover can increase the quality of the fruits. In addition, nanotechnology has had a positive impact on crop yield, nutritional value, fruit quality and can improve antioxidant activity. For these reasons, the use of beneficial elements such as silicon in the form… More >

  • Open Access

    ARTICLE

    Insecticidal Effect of Green Bimetallic Nanoparticles from Crotalaria longirostrata on Cotton Mealybug, Phenacoccus solenopsis

    Vianey Mendez-Trujillo1, Benjamín Valdez-Salas2, Mario Curiel-Alvarez2, Ernesto Beltran-Partida2, Arnoldo Alfaro-Corres3, Esaú Ruiz-Sanchez3, Gerardo Bautista-Trujillo4, Olivia Tzintzun Camacho5, Onecimo Grimaldo-Juarez5, Carlos Ceceña-Duran5, Carlos Ail-Catzin5, Daniel González-Mendoza5,*

    Journal of Renewable Materials, Vol.10, No.10, pp. 2543-2552, 2022, DOI:10.32604/jrm.2022.020965

    Abstract The present study was conducted to evaluate the impact of bimetallic nanoparticles (NPs) of copper (Cu) and zinc (Zn) from Crotalaria longirostrata on the insect mortality and cell viability of Phenacoccus solenopsis. The biosynthesis of bimetallic nanoparticles (Cu/Zn-NPs) from C. longirostrata was confirmed by the presence of a single peak around 378 nm. The hydrodynamic diameter of the Cu/Zn nanoparticles varied from 59 to 119 nm and their zeta potential was found to be −30.90 mV. The EDX analysis showed a strong signal for Cu and Zn (8 and 8.6 keV, respectively). The Cu/Zn-NPs showed an effective insecticide activity against P. solenopsis with 63%… More >

  • Open Access

    REVIEW

    Mesenchymal stem cell secretome and nanotechnology: Combining therapeutic strategies

    ADRIANA L. FERREIRA, GUSTAVO C. PARIS, ALINE DE A. AZEVEDO, ERIKA A. C. CORTEZ, SIMONE N. CARVALHO, LAIS DE CARVALHO, ALESSANDRA A. THOLE*

    BIOCELL, Vol.46, No.8, pp. 1807-1813, 2022, DOI:10.32604/biocell.2022.019363

    Abstract Mesenchymal stem cells (MSC) have pushed the field of stem cell-based therapies by inducing tissue regeneration, immunosuppression, and angiogenesis mainly through vesicles and soluble factors release (paracrine signaling). MSC-extracellular vesicles (MSC-EV) adaptable secretome and homing to injured sites allowed researchers to unlock a new era of cell-free based therapy. In parallel, nanoparticles (NP) have been explored in contributing to transport and drug delivery systems, giving drugs desired physical-chemical properties to exploit cell behavior. However, NPs can be quickly recognized by immune cells and cleared from circulation. In this viewpoint, we explore how combining both therapeutic strategies can improve efficacy and… More >

  • Open Access

    VIEWPOINT

    Impact of nanomaterials on plants: What other implications do they have?

    ANTONIO JUÁREZ-MALDONADO*

    BIOCELL, Vol.46, No.3, pp. 651-654, 2022, DOI:10.32604/biocell.2022.017350

    Abstract The use of nanomaterials has spread and has been applied in different industries, including agriculture. Here, the possibilities presented by NMs are very varied, from the biostimulation of favorable responses, or the control of pests and diseases, to the monitoring of characteristics of interest with the use of nanosensors. Particularly the biostimulation of agricultural crops with the use of nanomaterials is very relevant, since from this process stress tolerance, higher content of biocompounds, etc., can be induced. Although the positive impacts on crops are clear, there is not enough information to determine the long-term impacts, both on ecosystems and on… More >

  • Open Access

    REVIEW

    Nanotechnology-Based Advancements in Postharvest Management of Horticultural Crops

    Tarun Kumar Upadhyay1,*, V. S. Varun Kumar2, Amit Baran Sharangi3, Vijay J. Upadhye1, Fahad Khan4, Pratibha Pandey4, Mohammad Amjad Kamal5,6,7, Abrar Yasin Baba8 and Khalid Rehman Hakeem9,*

    Phyton-International Journal of Experimental Botany, Vol.91, No.3, pp. 471-487, 2022, DOI:10.32604/phyton.2022.017258

    Abstract Horticulture is a branch of Agricultural science where it is defined as the science and art of cultivating and handling fruits, vegetables, ornamental plants and several plants having unique medicinal and aromatic values. Horticultural crops provide farmers with high income and have good export quality, but they have a concern about postharvest losses. Hence, increasing productivity and decreasing post-harvest losses by using scientific studies and techniques like biotechnology and nanotechnology could be the simplest possible solution to the above-mentioned problems. Using nanotechnology which is having the characteristics of nanoparticles is proven to be very useful in science and technological applications.… More >

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