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    ARTICLE

    The Usefulness of Pretreatment MR-Based Radiomics on Early Response of Neoadjuvant Chemotherapy in Patients With Locally Advanced Nasopharyngeal Carcinoma

    Piao Yongfeng*†‡§1, Jiang Chuner*¶#1, Wang Lei*†‡§, Yan Fengqin*†‡§, Ye Zhimin*†‡§, Fu Zhenfu*†‡§, Jiang Haitao*,**††, Jiang Yangming‡‡, Wang Fangzheng*†‡§

    Oncology Research, Vol.28, No.6, pp. 605-613, 2020, DOI:10.3727/096504020X16022401878096

    Abstract The aim of this study was to explore the predictive role of pretreatment MRI-based radiomics on early response of neoadjuvant chemotherapy (NAC) in locoregionally advanced nasopharyngeal carcinoma (NPC) patients. Between January 2016 and December 2016, a total of 108 newly diagnosed NPC patients who were hospitalized in the Cancer Hospital of the University of Chinese Academy of Sciences were reviewed. All patients had complete data of enhanced MR of nasopharynx before treatment, and then received two to three cycles of TP-based NAC. After 2 cycles of NAC, enhanced MR of nasopharynx was conducted again. Compared with the enhanced MR images… More >

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