RENATA DA SILVA CARNEIRO¹, MATEUS HENRIQUE DE ALMEIDA DA COSTA¹, JOSé ZILTON LIMA VERDE SANTOS¹, VALDILéIA TEIXEIRA UCHôA², LUCIANO DA SILVA LOPES³, ANDERSON NOGUEIRA MENDES^1,*

BIOCELL, Vol.49, No.1, pp. 109-125, 2025, DOI:10.32604/biocell.2024.058405 - 24 January 2025

Abstract Neurodegenerative diseases are a major public health challenge, mainly affecting the elderly population and compromising their cognitive, sensory, and motor functions. Currently, available therapies focus on alleviating symptoms and slowing the progression of these conditions, but they do not yet offer a definitive cure. In this scenario, terpenes emerge as promising natural alternatives due to their neuroprotective properties. These compounds can reduce the formation of protein aggregates, neutralize free radicals, and inhibit pro-inflammatory enzymes, which are crucial factors in the development of neurodegenerative diseases. In addition, terpenes also play an important role in the… More >

YASHVI SHARMA¹, SHARDA RAY², SUJATA MOHANTY^1,*

BIOCELL, Vol.46, No.6, pp. 1435-1438, 2022, DOI:10.32604/biocell.2022.018612 - 07 February 2022

Abstract Neurodegenerative disorders are a vicious woe to the public health and wellness. Uncertainty in their underlying causes, lack of effective biomarkers for their early detection, existence of only supportive therapy, and their ever rising incidence creates an unmatched need for targeted therapies. Mesenchymal Stem Cells (MSCs) have found to be promising candidates for regenerative and remedial therapy in neurodegenerative disorders, however several biological risks and practical issues impede in their translational utility. Deriving from MSCs are certain Extracellular Vesicles (EVs), which aid in the paracrine action of MSCs and have lately gained the scientific interest More >