JIABAO WU1,2,#, XIAOHUA LIU1,2,#, LU HAN1,2, HUA NIE1,2, YUAN TANG1,2, YUNGE TANG1,3, GE SONG1,5, LIXIN ZHENG1,4, WEIBING QIN1,2,*
BIOCELL, Vol.46, No.4, pp. 1013-1023, 2022, DOI:10.32604/biocell.2022.016744
Abstract Piwi-interacting RNAs (piRNAs) is a novel class of non-coding RNAs. However, changes in piRNA expression profiles in recurrent spontaneous abortion (RSA) have not yet been investigated. The aim of this study was to identify differentially expressed piRNAs in deciduas of RSA patients. Decidua tissues were collected by curettage from recruited RSA patients and normal early pregnant (NEP) women with their informed consent. Small RNA sequencing was used to evaluate the differences in piRNA expression profiles between RSA and NEP. The present results demonstrated that the counts of total piRNA reads in RSA samples were increased compared with those in NEP… More >
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