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  • Open Access


    Enhanced Long Short Term Memory for Early Alzheimer's Disease Prediction

    M. Vinoth Kumar1,*, M. Prakash2, M. Naresh Kumar3, H. Abdul Shabeer4

    Intelligent Automation & Soft Computing, Vol.35, No.2, pp. 1277-1293, 2023, DOI:10.32604/iasc.2023.025591

    Abstract The most noteworthy neurodegenerative disorder nationwide is apparently the Alzheimer's disease (AD) which ha no proven viable treatment till date and despite the clinical trials showing the potential of preclinical therapy, a sensitive method for evaluating the AD has to be developed yet. Due to the correlations between ocular and brain tissue, the eye (retinal blood vessels) has been investigated for predicting the AD. Hence, en enhanced method named Enhanced Long Short Term Memory (E-LSTM) has been proposed in this work which aims at finding the severity of AD from ocular biomarkers. To find the level of disease severity, the… More >

  • Open Access


    Predicting Plaque Progression Using Patient-Specific Fluid-Structure-Interaction Models Based on IVUS and OCT Images with Follow-Up

    Xiaoya Guo1, Dalin Tang1,2,*, David Molony3, Chun Yang2, Habib Samady3, Jie Zheng4, Gary S. Mintz5, Akiko Maehara5, Jian Zhu6, Genshan Ma6, Mitsuaki Matsumura5, Don P. Giddens3,7

    Molecular & Cellular Biomechanics, Vol.16, Suppl.1, pp. 75-76, 2019, DOI:10.32604/mcb.2019.05743

    Abstract Atherosclerotic plaque progression is generally considered to be closely associated with morphological and mechanical factors. Plaque morphological information on intravascular ultrasound (IVUS) and optical coherence tomography (OCT) images could complement each other and provide for more accurate plaque morphology. Fluid-structure interaction (FSI) models combining IVUS and OCT were constructed to obtain accurate plaque stress/strain and flow shear stress data for analysis. Accuracy and completeness of imaging and advanced modeling lead to accurate plaque progression predictions.
    In vivo IVUS and OCT coronary plaque data at baseline and follow-up were acquired from left circumflex coronary and right coronary artery of one… More >

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