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    ABSTRACT

    Expression of Endothelial Tight Junction Protein Occludin under Mechanical Factors after Stent Implantation

    Junyang Huang1, Shuang Ge1, Yang Wang1, Ruolin Du1, Yazhou Wang1, Tieying Yin1, Guixue Wang1,*

    Molecular & Cellular Biomechanics, Vol.16, Suppl.2, pp. 138-139, 2019, DOI:10.32604/mcb.2019.07305

    Abstract Tight junctions are the most apical intercellular junctions of the lateral membrane in endothelial cells, regulating the paracellular material and energy exchange and maintain plasma membrane polarity. Occludin protein is one of the important proteins involved in endothelial tight junctions, and also closely related to the occurrence of atherosclerosis. Therefore, the study of occludin is valuable [1]. With the implantation of coronary stents, the integrity of the vascular endothelium is damaged and the local mechanical environment at the stent segment was changed [2]. The present study tried to explore the impact of mechanical stimulation after stent implantation on the expression… More >

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