DANIEL WAI-HUNG HO1,2,#, XUEYING LYU1,2,#, IRENE OI-LIN NG1,2,*
BIOCELL, Vol.45, No.6, pp. 1495-1500, 2021, DOI:10.32604/biocell.2021.017227
Abstract Oncovirus infection is crucial in human malignancies. Certain oncoviruses can lead to structural variations in
the human genome known as viral genomic integration, which can contribute to tumorigenesis. Existing viral integration
detection tools differ in their underlying algorithms pinpointing different aspects or features of viral integration
phenomenon. We discuss about major procedures in performing viral integration detection. More importantly, we
provide a technical update on Virus-Clip to facilitate its usage on the latest human genome builds (hg19 and hg38)
and the adoption of multi-thread mode for faster initial read alignment. By comparing the execution of Virus-Clip
using single-thread and multi-thread… More >
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