YONG RAO1,3,4, XIAO CHEN5,6, KAIYU LI1,3,4, MINHAI NIE1,3,4, XUQIAN LIU2,3,4,*
Oncology Research, Vol.33, No.3, pp. 577-590, 2025, DOI:10.32604/or.2024.053119
- 28 February 2025
Abstract Decorin (DCN) is primarily found in the connective tissues of various parts of the body, including the lungs, kidneys, bone tissue, aorta, and tendons. It is an important component of the extracellular matrix (ECM) and belongs to the class I small leucine-rich proteoglycans family. DCN is increasingly attracting attention due to its significant role in tumors, fibrotic diseases, and the regulation of vascular formation. Moreover, its anti-tumor properties have positioned it as a promising biomarker in the fight against cancer. Numerous studies have confirmed that DCN can exert inhibitory effects in various solid tumors, particularly… More >
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