Amina Mahreen¹, Fateh Mebarek-Oudina^2,3,4,*, Amna Ashfaq¹, Jawad Raza¹, Sami Ullah Khan⁵, Hanumesh Vaidya⁶

FDMP-Fluid Dynamics & Materials Processing, Vol.21, No.11, pp. 2829-2853, 2025, DOI:10.32604/fdmp.2025.072492 - 01 December 2025

Abstract Understanding the complex interaction between heat and mass transfer in non-Newtonian microflows is essential for the development and optimization of efficient microfluidic and thermal management systems. This study investigates the magnetohydrodynamic (MHD) thermosolutal convection of a Casson fluid within an inclined, porous microchannel subjected to convective boundary conditions. The nonlinear, coupled equations governing momentum, energy, and species transport are solved numerically using the MATLAB bvp4c solver, ensuring high numerical accuracy and stability. To identify the dominant parameters influencing flow behavior and to optimize transport performance, a comprehensive hybrid optimization framework—combining a modified Taguchi design, Grey… More >

Ricardo Dominico Da Silva^1,2, Jangkung Raharjo^1,3,*, Sudarmono Sasmono^1,3

Energy Engineering, Vol.122, No.12, pp. 5073-5090, 2025, DOI:10.32604/ee.2025.071545 - 27 November 2025

Abstract The rapid development of technology has led to an ever-increasing demand for electrical energy. In the context of Timor-Leste, which still relies on fossil energy sources with high operational costs and significant environmental impacts, electricity load forecasting is a strategic measure to support the energy transition towards the Net Zero Emission (NZE) target by 2050. This study aims to utilize historical electricity load data for the period 2013–2024, as well as data on external factors affecting electricity consumption, to forecast electricity load in Timor-Leste in the next 10 years (2025–2035). The forecasting results are expected… More >

Chi Zhang^1,#, Xi Huang^2,#, Cheng Hu¹, Bowen Tang¹, Jianjie Wu¹, Zhuolun Sun¹, Weian Zhu¹, Xiangfu Zhou¹, Hengjun Xiao^1,*, Hua Wang^1,*

Oncology Research, Vol.33, No.9, pp. 2331-2351, 2025, DOI:10.32604/or.2025.065119 - 28 August 2025

Abstract Background: U2AF homology motif kinase 1 (UHMK1) has been associated with RNA processing and protein phosphorylation, thereby influencing tumor progression. The study aimed to explore its regulatory mechanisms and biological functions in human prostate cancer (PCa). Methods: In this study, we systematically evaluated the expression and prognostic significance of UHMK1 in public databases, followed by validation through immunohistochemistry (IHC) in PCa specimens. Both gain-of-function and loss-of-function experiments were conducted to elucidate the role of UHMK1 in vitro and in vivo. Additionally, a series of molecular and biochemical assays were performed to investigate the regulatory mechanisms underlying UHMK1… More >

Kofi Bonsu^*, Olivier Bonin

Revue Internationale de Géomatique, Vol.34, pp. 639-654, 2025, DOI:10.32604/rig.2025.067000 - 11 August 2025

Abstract This study analyzes the spatial accessibility of key services in Caen, France, focusing on how different transport modes (car, bicycle, and public transit) influence access to essential services across the urban and suburban landscape. Indeed, the introduction of traffic restrictions in towns with low emission zones encourages a detailed study, on a fine spatial scale, of the differences in accessibility between different modes of transport, for different services and for different journey times. Using spatial analysis techniques, we examine accessibility patterns in relation to services such as shops, healthcare, education, and tourism, highlighting significant disparities… More >

Meida Chen¹, Tongfei Niu¹, Kai Gao², Zhanxiang Tan¹, Yuxin Zhao¹, Xiaogai Hou^1,*, Lili Guo^1,*

Phyton-International Journal of Experimental Botany, Vol.94, No.6, pp. 1921-1940, 2025, DOI:10.32604/phyton.2025.065738 - 27 June 2025

Abstract Floral scent serves as a key criterion for evaluating the ornamental value of flowering plants. Herbaceous peony (Paeonia lactiflora Pall.), a traditional Chinese ornamental species, is valued for its vibrant coloration, intricate floral morphology, and positive cultural symbolism. In this study, dynamic headspace adsorption coupled with gas chromatography-mass spectrometry was employed to analyze volatile organic compounds (VOCs) in flowers of 120 herbaceous peony cultivars at the half-opening stage. We detected 86 VOCs, comprising 25 aromatic compounds (79.70%), 21 hydrocarbons (10.51%), 29 terpenoids (8.37%), 7 fatty acid derivatives (1.03%), and 4 heterocyclic compounds (0.38%). The cultivar ‘Dr.… More >

Yuxin Yan, Huirui Wang, Jingyi Wen, Zerong Lan, Liang Wang^*

CMC-Computers, Materials & Continua, Vol.83, No.2, pp. 3059-3073, 2025, DOI:10.32604/cmc.2024.057949 - 16 April 2025

Abstract The development of artificial intelligence (AI) technologies creates a great chance for the iteration of railway monitoring. This paper proposes a comprehensive method for railway utility pole detection. The framework of this paper on railway systems consists of two parts: point cloud preprocessing and railway utility pole detection. This method overcomes the challenges of dynamic environment adaptability, reliance on lighting conditions, sensitivity to weather and environmental conditions, and visual occlusion issues present in 2D images and videos, which utilize mobile LiDAR (Laser Radar) acquisition devices to obtain point cloud data. Due to factors such as… More >

RIYAD F. ALZHRANI¹, LAMA BINOBAID², ABDULAZIZ A. ALORAINI¹, MESHAL S. ALSAHLI¹, AHMED H. BAKHEIT³, HANADI H. ASIRI³, SABRY M. ATTIA², ALI ALHOSHANI², GAMALELDIN I. HARISA^1,*

Oncology Research, Vol.33, No.4, pp. 919-935, 2025, DOI:10.32604/or.2024.054537 - 19 March 2025

Abstract Objective: Prostate cancer (PCA) is the second most widespread cancer among men globally, with a rising mortality rate. Enzyme-responsive lipid nanoparticles (ERLNs) are promising vectors for the selective delivery of anticancer agents to tumor cells. The goal of this study is to fabricate ERLNs for dual delivery of gefitinib (GF) and simvastatin (SV) to PCA cells. Methods: ERLNs loaded with GF and SV (ERLNGFSV) were assembled using bottom-up and top-down techniques. Subsequently, these ERLN cargoes were coated with triacylglycerol, and phospholipids and capped with chitosan (CS). The ERLNGFSV, and CS engineered ERLNGFSV (CERLNGFSV) formulations were… More > Graphic Abstract

Ruhul Amin¹, Md. Jamil Khan¹, Tonway Deb Nath¹, Md. Shamim Reza², Jungpil Shin^3,*

CMC-Computers, Materials & Continua, Vol.82, No.3, pp. 3907-3919, 2025, DOI:10.32604/cmc.2025.061645 - 06 March 2025

Abstract Heart disease includes a multiplicity of medical conditions that affect the structure, blood vessels, and general operation of the heart. Numerous researchers have made progress in correcting and predicting early heart disease, but more remains to be accomplished. The diagnostic accuracy of many current studies is inadequate due to the attempt to predict patients with heart disease using traditional approaches. By using data fusion from several regions of the country, we intend to increase the accuracy of heart disease prediction. A statistical approach that promotes insights triggered by feature interactions to reveal the intricate pattern… More >

Mohamed A.G. Hazber^1,*, Ebrahim Mohammed Senan^2,3, Hezam Saud Alrashidi¹

CMES-Computer Modeling in Engineering & Sciences, Vol.142, No.3, pp. 3229-3254, 2025, DOI:10.32604/cmes.2025.062302 - 03 March 2025

Abstract Hepatitis is an infection that affects the liver through contaminated foods or blood transfusions, and it has many types, from normal to serious. Hepatitis is diagnosed through many blood tests and factors; Artificial Intelligence (AI) techniques have played an important role in early diagnosis and help physicians make decisions. This study evaluated the performance of Machine Learning (ML) algorithms on the hepatitis data set. The dataset contains missing values that have been processed and outliers removed. The dataset was counterbalanced by the Synthetic Minority Over-sampling Technique (SMOTE). The features of the data set were processed… More >

Pieter C. van de Woestijne^1,*, Ingrid M. van Beynum², Kevin M. Veen³, Ad J. J. C Bogers¹

Congenital Heart Disease, Vol.19, No.6, pp. 593-601, 2024, DOI:10.32604/chd.2025.060607 - 27 January 2025

Abstract Background: Construction of a central shunt by connection of hypoplastic true pulmonary arteries to the ascending aorta (AO) can be performed as a first step in staged repair of pulmonary atresia with ventricular septal defect and major aorto-pulmonary collateral arteries (PA-VSD-MAPCAs) intended to promote growth and development of the central pulmonary arteries. Methods: To determine early and intermediate-term growth of true pulmonary arteries after their connection to the AO as a first step in staged repair of PA-VSD-MAPCAs, we reviewed all angiographic studies and CT imaging of patients, treated in our tertiary referral center in… More > Graphic Abstract