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  • Open Access

    ARTICLE

    A Data-Driven Method for Rapid Prediction of Polarization Curves in Proton Exchange Membrane Electrolysis Cell

    Rongyu Yang1, Qiaoxin Li2, Hao Cheng1,*, Rui Gao1, Yongli Li1,*

    Energy Engineering, Vol.123, No.9, 2026, DOI:10.32604/ee.2026.082907 - 06 August 2026

    Abstract The prediction of the steady-state performance of the electrolysis cell is not only crucial for evaluating the rationality of its design and operational benchmarks, but also provides an important foundation for understanding its dynamic response behavior. This paper presents an efficient data-driven method based on three-dimensional two-phase numerical simulation and machine learning (ML) to rapidly predict the steady-state performance of proton exchange membrane electrolysis cells (PEMEC) under multi-physics field coupling conditions. The framework is based on three key operating parameters—temperature, pressure, and inlet flow velocity. A polarization curve dataset was constructed through multi-condition numerical simulations,… More > Graphic Abstract

    A Data-Driven Method for Rapid Prediction of Polarization Curves in Proton Exchange Membrane Electrolysis Cell

  • Open Access

    ARTICLE

    Unsafe Sanitation and the Global Incidence of Congenital Heart Disease: A Spatial Correlation Analysis

    Yi Shen1,2,3,#, Zeye Liu4,#, Jing Xie5,#, Xuanqi An6,7,8,#, Zeyu Jing1,2,3, Wenchuan Liao1,2,3, Yifan Zhu1,2,3, Chenyu Jiang1,2,3, Xingliang Zhou1,2,3, Xu Huang1,2,3, Tianyu Liu1,2,3, Jian Liu1,2,3, Yuxi Ji1,2,3, Yi Yan1,3, Bei Feng1,3, Yiwei Liu1,2,3, Yi Shi4,*, Yanjun Sun2,*, Hao Zhang1,2,3,*

    Structural and Congenital Heart Disease, Vol.21, No.3, 2026, DOI:10.32604/schd.2026.085942 - 31 July 2026

    Abstract Background: Congenital heart disease (CHD) is the most common congenital anomaly worldwide, yet the contribution of environmental factors to its global geographic variation remains incompletely understood. We aimed to systematically identify environmental factors associated with CHD incidence using an integrated framework combining machine learning and spatial epidemiology. Methods: Country-level data were obtained from the Global Burden of Disease (GBD) 2021 study. Boruta algorithm-based feature selection and random forest SHAP value ranking were applied to identify environmental factors associated with CHD incidence. Negative binomial regression was used to evaluate the associations between selected variables and CHD incidence.… More >

  • Open Access

    ARTICLE

    A Hybrid MZOA-PSO Optimized Cascaded PI(1+DD)-PI-PID Controller for Frequency Stability of Interconnected Power Systems with Renewable Energy and Electric Vehicles

    AL-Wesabi Ibrahim1, Hassan M. Hussein Farh2,*, Jiazhu Xu1,*, Mohamad A. Alawad2, Ahmed Alqurashi3, Abdullrahman A. Al-Shamma’a2

    CMES-Computer Modeling in Engineering & Sciences, Vol.148, No.1, 2026, DOI:10.32604/cmes.2026.081371 - 27 July 2026

    Abstract Load frequency control (LFC) in interconnected power systems has always been a challenging task in the presence of uncertainty and variability in the power systems arising primarily due to the integration of renewable energy sources and the impact of electric vehicles on the power system. Although various PI/PID and other advanced control strategies have been employed for LFC in power systems, the existing methods have shown some limitations in terms of dynamic flexibility and robustness in the presence of nonlinearities and couplings in the power systems. Moreover, the optimization methods employed for the tuning of… More >

  • Open Access

    ARTICLE

    Isoliquiritigenin Suppresses Oral Squamous Cell Carcinoma Progression by Targeting FABP5-Mediated Lipid Metabolism: Association with the circPOLB/miR-548ae-3p/C-MYC Axis

    Liang Li1,#, Hong Deng2,#, Zhiyong Li2, Yu Li2, Lingrui Liu2, Lan Xie2,*, Yue Chen3,*

    Oncology Research, Vol.34, No.8, 2026, DOI:10.32604/or.2026.081109 - 16 July 2026

    Abstract Objectives: Oral squamous cell carcinoma (OSCC) is a common and deadly cancer affecting the oral cavity. This study aims to explore the regulatory role and molecular mechanism of miR-548ae-3p in OSCC proliferation, invasion, and lipid metabolism, as well as the therapeutic potential of isoliquiritigenin (ISL) targeting OSCC lipid metabolism. Methods: Expression levels of miR-548ae-3p were measured in OSCC cell lines and normal oral keratinocytes using real-time quantitative polymerase chain reaction. Functional assays, such as cell counting Kit-8 proliferation and Transwell invasion assays, evaluated the effects of miR-548ae-3p overexpression in CAL-27 and SCC-25 cells. Bioinformatic prediction and… More >

  • Open Access

    ARTICLE

    Development of Calopogonium mucunoides PEGylated Solidified Reverse Micellar Suspensions: Polymer-Matrix Design for Sustainable Wound Application

    Edith O. Diovu1, Calister E. Ugwu2,*, Eunice N. Anaele3,*, Samuel WisdomofGod Uzondu4, Ogochukwu N. Umeh2, Iheanacho O. Enyum2, Kingsley C. Eze2, Godswill C. Onunkwo2, Anthony A. Attama5

    Journal of Polymer Materials, Vol.43, No.2, 2026, DOI:10.32604/jpm.2026.077511 - 30 June 2026

    Abstract Polymer-lipid hybrid-based solidified reverse micellar suspensions (SRMs) have gained increasing interest for topical drug delivery due to their ability to enhance solubility, stabilize bioactive compounds, and achieve sustained skin permeation. In this study, PEGylated SRMs were developed using a beeswax: Phospholipon 90H lipid matrix to enhance the solubility, stability, bioavailability, and wound-healing properties of a lipophilic extract of Calopogonium mucunoides (CM). PEG: lipid matrix ratios (1:0, 0:1, 1:1, 1:2, 1:3) were formulated and designated as CM1–CM5, with an unloaded matrix (CM6) as control. Physicochemical characterization included encapsulation efficiency (EE%), spreadability, pH, viscosity, Fourier transform infrared spectroscopy… More >

  • Open Access

    ARTICLE

    Enhanced-WOA Optimized FOPID Controller for Energy-Efficient Path-Tracking Robot

    Hooi Hung Tang, Te Meng Ting, Nur Syazreen Ahmad*

    CMES-Computer Modeling in Engineering & Sciences, Vol.147, No.3, 2026, DOI:10.32604/cmes.2026.080428 - 30 June 2026

    Abstract In industrial and service robotics, autonomous mobile robots must achieve accurate trajectory tracking while maintaining low energy consumption to avoid frequent recharging and performance degradation. Energy efficiency is particularly critical because locomotion accounts for 45%–65% of total power consumption, directly limiting operational range and autonomy. This paper proposes an energy-aware trajectory tracking framework that optimizes a fractional-order proportional-integral-derivative (FOPID) controller using an Enhanced Whale Optimization Algorithm (E-WOA). The key contributions are threefold: (1) the E-WOA hybridizes Differential Evolution (DE)’s global exploration with WOA’s local exploitation to overcome premature convergence in high-dimensional FOPID parameter spaces; (2)… More >

  • Open Access

    ARTICLE

    Structural Design and Control of the Intelligent Hook for Horizontal Rotating Flexible Lifting Straps

    Mingliang Yang1, Yuyu Miao1,*, Xijun Xu2, Heng Yang1, Dong Qing1, Keyuan Zhao1

    Structural Durability & Health Monitoring, Vol.20, No.4, 2026, DOI:10.32604/sdhm.2026.078754 - 30 June 2026

    Abstract The autonomous grasping of flexible slings is a pivotal challenge for unmanned crane systems, primarily stemming from the slings’ geometric indeterminacy, material compliance under load, and stochastic initial pose relative to the hook. To address this challenge, we propose an intelligent hook system featuring a novel compound mechanical architecture. This architecture integrates a horizontal slewing mechanism for in-plane alignment with a self-locking worm-gear drive for secure grasping. A coordinated control strategy, employing a Fuzzy PID algorithm, ensures robust dynamic performance under variable loading conditions. Finite element analysis confirms structural integrity under a rated load of More >

  • Open Access

    ARTICLE

    In Silico Prioritization of Plant Growth Regulators as Candidate Modulators of Microalgal Lipid Biosynthesis for Biofuel Production

    Hanane Oucif1,2,*, Miloud Benaissa1,2, Leila Saddikioui3, Nadia Y. Asfouri3, Meriem F. Meliani1, Zineb Belhamra1,2, Djilali Baghdadi1,2

    Phyton-International Journal of Experimental Botany, Vol.95, No.6, 2026, DOI:10.32604/phyton.2026.080926 - 29 June 2026

    Abstract Enhancing lipid productivity in microalgae is a critical goal for advancing sustainable biofuel production. Among emerging strategies, the supplementation of plant growth regulators (PGRs) has gained attention as a potential approach for modulating microalgal metabolism. This in silico study evaluated the predicted binding of sixty-five PGRs from 11 chemical classes to five microalgal enzymes associated with lipid biosynthesis, (FabD, KASII, FabG, FATA, and GPAT) using an integrative computational workflow combining virtual screening, molecular docking, molecular dynamics (MD) simulations, and density functional theory (DFT) calculations. Structure-based screening identified fifty-eight compounds with docking scores below −5.0 kcal/mol, consistent… More >

  • Open Access

    CASE REPORT

    Clean intermittent catheterization reverses hydronephrosis in a child with congenital nephrogenic diabetes insipidus: a case report

    Jianlin Xie1,#, Jingde Wu1, Qingwei Zhang1, Yuanqi Guo1, Xiande Huang2,*

    Canadian Journal of Urology, Vol.33, No.3, pp. 723-728, 2026, DOI:10.32604/cju.2026.075856 - 29 June 2026

    Abstract Background: Congenital nephrogenic diabetes insipidus (CNDI) is most frequently caused by mutations in the AVPR2 gene. Patients exhibit persistent polyuria due to renal insensitivity to antidiuretic hormone. Chronic high urine output predisposes to bladder dysfunction and upper urinary-tract dilatation, notably hydronephrosis. Although pharmacotherapy can partially reduce urine volume, its capacity to reverse established hydronephrosis is limited. Clean intermittent catheterization (CIC), a mainstay in managing neurogenic bladder, warrants investigation regarding its utility in CNDI-associated hydronephrosis.
    Case Description: A 9-year-old Chinese boy presented with lifelong polydipsia and polyuria, with a peak 24-h urine output of approximately 7100 mL. Renal ultrasonography… More >

  • Open Access

    ARTICLE

    Associations of Mentally Active Versus Passive Sedentary Behavior with Smartphone Addiction in Adults

    Abdulaziz A. Masoud1,2,*

    International Journal of Mental Health Promotion, Vol.28, No.5, 2026, DOI:10.32604/ijmhp.2026.078593 - 28 May 2026

    Abstract Background: Sedentary behavior (SB) has been linked to problematic smartphone use: however, whether different types of SB differentially relate to smartphone addiction risk remains unclear. This study aimed to examine the prevalence of smartphone addiction risk and the independent associations of mentally active and mentally passive SB—across total, weekday, and weekend estimates—with smartphone addiction scores among Saudi adults. Methods: This cross-sectional, web-based study recruited adults aged 18–65 years residing in Saudi Arabia through social media platforms. After excluding participants with missing anthropometric data, implausible body mass index (BMI) values, or total SB >24 h/day, 1037 participants… More >

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