Peng Wang, Haiyang Zhang, Zilian Cui, Xunbo Jin*, Dong Zhang*
Oncologie, Vol.23, No.2, pp. 259-268, 2021, DOI:10.32604/Oncologie.2021.015503
Abstract Urothelial carcinoma of bladder (UCB) is a common urological malignancy in the world, but its progression
mechanism remains unclear. MiR-612 was found as an anti-tumor factor in multiple types of cancer, while
few studies have revealed its functions in UCB cells. Based on this, UCB cells such as HTB-9 and HTB-4, and
normal urothelial of bladder cells such as SV-Huc1, were used as subjects in this study. Western blot, qRTPCR, CCK-8 assay and transwell assay were used to assess functions of miR-612 in UCB cells. The database,
miRWalk, was used to search for potential targets of miR-612, and dual-luciferase reporter… More >
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