HAZAEL RAMIRO CEJA-GÁLVEZ1, ERANDIS DHENI TORRES-SÁNCHEZ1, JUAN HERIBERTO TORRES-JASSO2, ARTURO VILLALOBOS ORNELAS1, JOEL SALAZAR-FLORES1,*
BIOCELL, Vol.44, No.3, pp. 363-370, 2020, DOI:10.32604/biocell.2020.09147
Abstract Paraoxonase-1 (PON1) is an important enzyme in various pathologies such as pesticide poisoning, diabetes,
atherosclerosis, neuronal disorders, and cancer, due to its multifunctional activity since it acts on different metabolites.
However, one of its main functions is the hydrolysis of organophosphate (OP) compounds from pesticides that cause
fatal poisoning at the level of the central nervous system (CNS). The objective of this review was to investigate whether
the structure, genetics, and function of PON1 affect the metabolism of organophosphate pesticides or other
abnormalities. Information was selected from articles in the database PubMed–NCBI (https://www.ncbi.nlm.nih.gov/
pubmed/) with a publication date between 2011… More >
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