Xuelian Du1,#, Hao Shi2,#, Haiyan Liu1, Linghua Zhou1, Anqun Xie1, Jufang Guo1,*
Oncologie, Vol.24, No.4, pp. 769-787, 2022, DOI:10.32604/oncologie.2022.026248
Abstract Background: Gestational diabetes mellitus (GDM) affects the health of numerous women around the world. A
recent study has shown that GDM is associated with an increased incidence of cancer. In this study, we aimed
to explore the possible shared mechanisms and potential common therapeutic targets between GDM and cancer.
Methods: The limma package was used to identify differentially expressed genes (DEGs) in GDM. The Cytoscape
plugin cytoHubba was used to screen hub genes. The CIBERSORT algorithm was used to explore the correlation
between hub genes and immunity. Cox regression analysis was used to assess the relationship between protein
tyrosine kinase… More >
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