ROBERTO YUNES, PEDRO FERNÁNDEZ, GUSTAVO F. DONCEL, ANÍBAL A. ACOSTA

BIOCELL, Vol.29, No.3, pp. 287-293, 2005, DOI:10.32604/biocell.2005.29.287

Abstract Our objective was to determine the effect of phosphodiesterase (PDE) inhibition on: 1) tyrosine phosphorylation of human spermatozoa at the tail level; and 2) sperm motion parameters and hyperactivated motility. The study was conducted with normozoospermic and asthenozoospermic samples incubated under in vitro capacitating conditions. The main outcome measures were computer-assisted sperm motion analysis and fluorescent immunodetection of phosphotyrosine-containing proteins. Pentoxifylline (PTX) was used as PDE inhibitor because of its wide use in the clinic. PTX-treatment significantly increased sperm velocity, hyperactivated motility and tyrosine-phosphorylation, both in normo and asthenozoospermic samples. Tyrosine-phosphorylation of tail proteins was highly conspicuous in both types… More >

P. Muddasani¹, H-J. Im¹

Molecular & Cellular Biomechanics, Vol.3, No.4, pp. 159-161, 2006, DOI:10.32604/mcb.2006.003.159

Abstract This article has no abstract. More >

Abdulkareem Younis SULEIMAN¹, Intisar Salim PITY², Mohammed R MOHAMMED², Bashar Abduljabar HASSAWI²

BIOCELL, Vol.43, No.3, pp. 175-181, 2019, DOI:10.32604/biocell.2019.06884

Abstract Ovarian lesions are commonly encountered pathologies that cannot be categorized clinicoradiologically. Definite diagnosis is of great importance for therapeutic and prognostic purposes. Histopathology gives accurate diagnosis in most cases. Few cases need supportive tests like immunohistochemistry. Objective: to study the histomorphological diversity of ovarian lesions, their age and location in North of Iraq (Mosul and Duhok). Patients and methods: In the period extended from January 2008 to December 2011, 161 cases of ovarian lesions were collected from pathology departments in Azadi General Hospital “Duhok” and Al-Jamhori Teaching Hospital “Mosul”. Automated tissue processor was used for histologic study and Streptavidin-biotin method… More >

Junhao Yang¹, Chunxiao Chen^1,*, Qingyang Zang¹, Jianfei Li¹

Molecular & Cellular Biomechanics, Vol.15, No.4, pp. 203-214, 2018, DOI:10.32604/mcb.2018.03824

Abstract Pathological slide is increasingly applied in the diagnosis of breast tumors despite the issues of large amount of data, slow viewing and high subjectivity. To overcome these problems, a micrograph recognition method based on convolutional neural network is proposed for pathological slide of breast tumor. Combined with multi-channel threshold and watershed segmentation, a sample database including single cell, adhesive cell and invalid cell was established. Then, the convolution neural network with six layers is constructed, which has ability to classify the stained breast tumor cells with accuracy of more than 90%, and evaluate the proliferation level with relative error of… More >

C.M. Müller-Karger¹, C.González², M.H.Aliabadi³, M.Cerrolaza⁴

CMES-Computer Modeling in Engineering & Sciences, Vol.2, No.1, pp. 1-14, 2001, DOI:10.3970/cmes.2001.002.001

Abstract In this paper, a three-dimensional Boundary Element model of the proximal tibia of the human knee is described and stresses and displacements in the tibial plateau under static loading are computed. The geometry is generated via three-dimensional reconstruction of Computerized Tomographies and Magnetic Resonance Imaging. Various models of different lengths from the tibia plateau are calculated. The BEM results are compared with a Finite Element model having the same geometry and tibia FE models available in the literature. Also reported are investigations of some pathological situations, including fractures. The results of the comparisons show that BEM is an efficient and… More >

Xinfang Wang¹, Lianqing Hong², Xi Wu³, Jia He³, Ting Wang^3,4,*, Hongbo Li⁵, Shaoling Liu⁶

CMC-Computers, Materials & Continua, Vol.61, No.1, pp. 141-154, 2019, DOI:10.32604/cmc.2019.06030

Abstract An ultrasonic nomogram was developed for preoperative prediction of Castleman disease (CD) pathological type (hyaline vascular (HV) or plasma cell (PC) variant) to improve the understanding and diagnostic accuracy of ultrasound for this disease. Fifty cases of CD confirmed by pathology were gathered from January 2012 to October 2018 from three hospitals. A grayscale ultrasound image of each patient was collected and processed. First, the region of interest of each gray ultrasound image was manually segmented using a process that was guided and calibrated by radiologists who have been engaged in imaging diagnosis for more than 5 years. In addition,… More >