CINZIA SIGNORINI^*, GIULIA COLLODEL, ELENA MORETTI

BIOCELL, Vol.46, No.4, pp. 881-884, 2022, DOI:10.32604/biocell.2022.018062

Abstract The manuscript deals with our studies and experiences in the assessment of cytoskeleton in different cellular models and situations. The immunofluorescent study of several cytoskeletal proteins was relevant in the evaluation of a therapy for osteoarthritis, in case of alkaptonuria and in testing the efficacy of docetaxel in neuroblastoma cancer cells leading to apoptosis. A relevant part of our experience focus on the study of cytoskeleton in seminiferous epithelium and spermatozoa, identifying alterations affecting blood-testis barrier after a silver nanoparticle treatment, chromosomal segregation in case of varicocele, sperm motility and diagnosing systematic sperm defects as “Primary ciliary dyskinesia” and “Dysplasia… More >

C.M. Müller-Karger¹, C.González², M.H.Aliabadi³, M.Cerrolaza⁴

CMES-Computer Modeling in Engineering & Sciences, Vol.2, No.1, pp. 1-14, 2001, DOI:10.3970/cmes.2001.002.001

Abstract In this paper, a three-dimensional Boundary Element model of the proximal tibia of the human knee is described and stresses and displacements in the tibial plateau under static loading are computed. The geometry is generated via three-dimensional reconstruction of Computerized Tomographies and Magnetic Resonance Imaging. Various models of different lengths from the tibia plateau are calculated. The BEM results are compared with a Finite Element model having the same geometry and tibia FE models available in the literature. Also reported are investigations of some pathological situations, including fractures. The results of the comparisons show that BEM is an efficient and… More >