GAGANJOT GUPTA1, DEEPAK BANSAL2, ANSHULA SHARMA1, TAWSEEF AHMAD1, ATUL SACHDEV2, AJAZ AHMAD3, HAMED A. EL-SEREHY4, BALJINDER KAUR1,*
BIOCELL, Vol.45, No.5, pp. 1299-1311, 2021, DOI:10.32604/biocell.2021.015411
Abstract Helicobacter pylori infection has been significantly linked to Peptic Ulcer Disease and Gastric Cancer.
Metabolomic fingerprinting may offer a principal way of early diagnosis and to understand the molecular mechanism
of H. pylori-induced pathogenicity. The rationale of the study is to explore the underlying distinct metabolic
mechanisms of H. pylori-induced PUD and to identify potential biomarkers for disease diagnosis and associated risks
using Gas chromatography/mass spectrometry. GC/MS-based analytical method was used to compare metabolic
profiles of healthy controls (N = 20) and peptic ulcer patients (N = 45). Acquired metabolomic data were analyzed by
constructing a diagnostic model using principal… More >
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