YANGUO PENG1,#, WEI LI2,#, SHUIYU CHEN1, WANGCHUN WU1, ZHANFANG SHANG1,*
BIOCELL, Vol.45, No.1, pp. 57-64, 2021, DOI:10.32604/biocell.2021.011756
Abstract Peripheral nerve injury is a common neurodegenerative disease, which causes disability and a huge economic
burden for patients. MicroRNAs (miRNAs) have been acknowledged as major regulators and therapeutic targets of
neurological disease. Thus, the functional studies of miRNAs in neurological disease will contribute to discover new
therapeutic targets for peripheral nerve injury. Sprague Dawley rats treated sciatic nerve surgical injury were regarded
as peripheral nerve injury model in vivo. The expression of miR-494-3p and Kruppel like factor7 (KLF7) were
measured by Real-time quantitative polymerase chain reaction (RT-qPCR) assay. In addition, western blot analysis
was conducted to measure the protein levels… More >
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