Carmelo Libetta1, Pasquale Esposito1, Vincenzo Sepe1, Carlo Guastoni2, Manuela Zucchi3, Federica Meloni4, Antonio Dal Canton1
European Cytokine Network, Vol.22, No.1, pp. 24-31, 2011, DOI:10.1684/ecn.2011.0280
Abstract Background. Peritoneal dialysis (PD) is associated with a depression of T cell function, as suggested by
the impaired production of cytokines by Th cells collected from PD patients. Although treatment biocompatibility
could be implicated in this immune dysfunction, it has been poorly investigated, thus far. Therefore, we undertook
a study aiming to analyze the effects of different peritoneal dialysis fluids on the Th1/Th2 balance in PD patients.
Methods. Twenty three patients on continuous ambulatory peritoneal dialysis (CAPD) were evaluated. Seven patients
were on CAPD with icodextrin solution (ICO-PD), seven with glucose and lactate/bicarbonate-buffered solution
(LAC/BIC-PD),… More >
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