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    ARTICLE

    Effect of peroxiredoxin 6 on total and progressive motility of human spermatozoa after cryopreservation

    TIECHENG SUN1,#, LUYANG CHENG2,#, JING MA3,#, SHANJIE ZHOU1, YANDONG ZHANG1, WENDI ZHOU4, SHOULONG DENG5, SHUSONG WANG3,*, TIAN LI1,6,*

    BIOCELL, Vol.44, No.3, pp. 323-327, 2020, DOI:10.32604/biocell.2020.011890

    Abstract Sperm cryopreservation is useful in assisted reproductive technology and male fertility preservation. However, freezing and thawing significantly reduces the total and progressive motility of human spermatozoa. In the present study, we explored the effects of peroxiredoxin 6 (PRDX6) on total and progressive motility of human spermatozoa after cryopreservation. Semen samples of 20 males with normal parameters were collected and frozen in media supplemented with different concentrations of PRDX6 (0 mM, 10−5 mM, 10−7 mM, and 10−9 mM, respectively). Postthaw total and progressive motility of sperms were measured. The results showed that in comparison with 0 mM, the concentrations of 10−5More >

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