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    REVIEW

    Application of photodynamic therapy in cancer: challenges and advancements

    ZIXUAN WANG1,#, HONGMEI PENG2,#, WEI SHI4,#, LU GAN1, LIPING ZHONG1, JIAN HE1, LINLIN XIE1, PAN WU1, YONGXIANG ZHAO1, ZHIMING DENG3,*, HONGLIANG TANG4, YONG HUANG1,3,*

    BIOCELL, Vol.45, No.3, pp. 489-500, 2021, DOI:10.32604/biocell.2021.014439

    Abstract Although great achievements have been made in the past decades in medicine, cancer remains a worldwide public health issue. Surgery is usually accompanied by shortcomings such as residual lesions and poor treatment effects, and the successive appearance of other treatment methods, such as radiotherapy and chemotherapy, has not changed the postoperative recurrence rate, toxicity, and side effects. However, the advent of photodynamic therapy has greatly improved this situation. Photodynamic therapy is an emerging tumor diagnosis and treatment technology with good application prospects, photodynamic therapy uses a specific wavelength of light to excite a photosensitizer to generate reactive oxygen species, damage… More >

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