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  • Open Access

    ARTICLE

    Valorisation of Northern Moroccan Centaurium erythraea: Targeted Phytochemistry, Antioxidant, Antimicrobial Efficacy and Drug Likeness Benchmarking

    Yousra Hammouti1,2,*, François Mesnard2, Oussama Khibech3, Mohamed Taibi1, Yousra Belbachir3, El Hassania Loukili4, Reda Bellaouchi5, Abdeslam Asehraou5, Mohamed Addi1,*

    Phyton-International Journal of Experimental Botany, Vol.94, No.11, pp. 3563-3583, 2025, DOI:10.32604/phyton.2025.071139 - 01 December 2025

    Abstract Centaurium erythraea Rafn (“Gosset El Haya”) has long been prized in North African folk medicine, yet Moroccan chemobiological data remain scarce. Ethanol extracts of northern Moroccan aerial parts were profiled by high-performance liquid chromatography (HPLC) and found rich in phenolics, dominated by 4-hydroxybenzoic acid (57.8%) and naringin (10.3%). The extract exhibited strong antioxidant power in the 2,2-diphenyl-1-picrylhydrazyl (DPPH) radical-scavenging assay, with a half-maximal inhibitory concentration (IC50) of ≈74 µg mL−1, and a total antioxidant capacity (TAC) of ≈201 µg mL−1 and selective antimicrobial activity, sharply inhibiting Aspergillus niger, Penicillium digitatum, and Rhodotorula glutinis while sparing Staphylococcus aureus. In-silico absorption, distribution, metabolism,… More >

  • Open Access

    ARTICLE

    Thymus serpyllum L. Essential Oil: Phytochemistry and in Vitro and in Silico Screening of Its Antimicrobial, Antioxidant and Anti-Inflammatory Properties

    Samiah Hamad Al-Mijalli1, Hanae Naceiri Mrabti2, Amine Elbouzidi3,*, Naglaa S. Ashmawy4,5, Amine Batbat6, Emad M. Abdallah7, Wafa Laaboudi8, Mohammed Aladhadh9, Fahad M. Alshabrmi10, Sulaiman Mohammed Alnasser11, Mohamed Addi3, Naoufal El Hachlafi12

    Phyton-International Journal of Experimental Botany, Vol.94, No.1, pp. 209-227, 2025, DOI:10.32604/phyton.2025.060438 - 24 January 2025

    Abstract Thymus serpyllum L., often known as wild thyme, has been used since ancient times due to its multifaceted culinary and medicinal attributes. It is usually utilized in folk medicine to manage different health issues. This work aimed to investigate the chemical composition and biological characteristics of T. serpyllum essential oil (EO), including its antimicrobial, antioxidant, and anti-inflammatory capabilities. Moreover, we have prompted an in-silico simulation to reveal the underlying mode of action of these properties. The chemical characterization of T. serpyllum (EO) by Gas Chromatography-Mass Spectrometry (GC-MS) indicated sabinene (17.33%), terpinen-4-ol (11.73%), phellandral (13.18%), and thymol (10.54%) as main… More >

  • Open Access

    REVIEW

    Phytochemistry and ethnomedicinal qualities of metabolites from Phyllanthus emblica L.: A review

    VIJAY KUMAR1,#, PRAVEEN C. RAMAMURTHY2,#, SIMRANJEET SINGH2,#, DALJEET SINGH DHANJAL3, PARUL PARIHAR4, DEEPIKA BHATIA5, RAM PRASAD6,*, JOGINDER SINGH7,*

    BIOCELL, Vol.47, No.5, pp. 1159-1176, 2023, DOI:10.32604/biocell.2023.022065 - 10 April 2023

    Abstract Phyllanthus emblica or Indian gooseberry is an integrated part of Ayurvedic and Traditional Chinese Medicines. For several decades, the well-known ancient herb has been extensively utilized in traditional medicine to cure diseases like fever, diabetes, constipation, jaundice, ulcers, biliousness, anemia, anorexia, and dyspepsia. In the traditional system, Indian gooseberry has various ethnomedicinal applications. In the Ayurvedic system, different methods of administration (anupan) have shown different ethnomedicinal properties of Indian gooseberry. Seventy well-known chemical components in Indian gooseberry have been identified through phytochemical evaluation, among which the flavonoids and phenols are most prominent. From the toxicity perspective,… More >

  • Open Access

    ARTICLE

    A revision of Eupatorium (Compositae: Eupatorieae) from Michoacan

    Garcia Sanchez E1,2, CB Ramirez Lopez1,2, REN del Rio Torres2, MM Martinez Pacheco2

    Phyton-International Journal of Experimental Botany, Vol.80, pp. 139-146, 2011, DOI:10.32604/phyton.2011.80.139

    Abstract An important study in species of the genus Eupatorium, that inhabits other parts of the world, was conducted in the search for new molecules with pharmacological activities, thus showing that it is a potential source of novel secondary metabolites. We reviewed the number of Eupatorium species that have been described in the State of Michoacan, and that can be available for harvesting, to make a phytochemical screening. It was found that 69 Eupatorium spp are growing in 69% of the Michoacan territory. Within this group there are ten species used in Mexican traditional medicine. It was evident More >

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