Xiuchun ZHANG
BIOCELL, Vol.43, No.4, pp. 313-319, 2019, DOI:10.32604/biocell.2019.07973
Abstract To investigate the effects of polydatin on the proliferation, migration, and invasion of ovarian cancer, the
change of proliferative ability, migration ability, and invasive ability of human ovarian cancer cell OVCAR-3, A2780,
and HO-8910 was detected by using polydatin and up-regulating PI3K. The anticancer activity and mechanism of
polydatin in ovarian cancer were analyzed. Polydatin could effectively inhibit the proliferation, migration, and invasion
of OVCAR-3, A2780, and HO-8910, and inhibit the expression of PI3K protein. After the expression level of PI3K
protein was up-regulated, the inhibitory effect of polydatin on the proliferative ability, migration ability, and invasive
ability of OVCAR-3,… More >
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