WANTONG LIU1,#, DANYANG CHEN1,#, JINGYAO SU1,#, RUILIN ZHENG1,#, RAN KONG1, BING ZHU1, HAO DONG2,*, YINGHUA LI1,*
BIOCELL, Vol.47, No.1, pp. 187-194, 2023, DOI:10.32604/biocell.2022.023030
Abstract Liver cancer is the seventh most common malignant tumor in the world and is the second highest cause of death
due to cancer. Quercetin, a flavonoid with low toxicity, widely exists in various fruits and vegetables. It has the potential to be
a therapeutic agent against various cancers. This study aimed to demonstrate the anti-tumor effect of quercetin on HepG2
cells. Quercetin suppressed the HepG2 cell proliferation in a dose-dependent manner in cell viability assay. Induction of cell
apoptosis was confirmed by apoptotic cells population (sub-G1 peak) detected by flow cytometer. A decrease in
mitochondrial membrane potential and caspase-3 activation… More >
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