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  • Open Access

    ARTICLE

    Galectin 2 regulates JAK/STAT3 signaling activity to modulate oral squamous cell carcinoma proliferation and migration in vitro

    XINRU FENG1, LI XIAO2,*

    BIOCELL, Vol.48, No.5, pp. 793-801, 2024, DOI:10.32604/biocell.2024.048395

    Abstract Background: Galectin 2 (LGALS2) is a protein previously reported to serve as a mediator of disease progression in a range of cancers. The function of LGALS2 in oral squamous cell carcinoma (OSCC), however, has yet to be explored, prompting the present study to address this literature gap. Methods: Overall, 144 paired malignant tumor tissues and paracancerous OSCC patient samples were harvested and the LGALS2 expression levels were examined through qPCR and western immunoblotting. The LGALS2 coding sequence was introduced into the pcDNA3.0 vector, to enable the overexpression of this gene, while an LGALS2-specific shRNA and corresponding controls were also obtained.… More >

  • Open Access

    ARTICLE

    Transcriptome Analysis of Inflorescence Development at the Five-Leaf Stage in Castor (Ricinus communis L.)

    Yong Zhao1,#, Yaxuan Jiang3,#, Li Wen1, Rui Luo2, Guorui Li2, Jianjun Di2, Mingda Yin2, Zhiyan Wang2, Fenglan Huang2,4,5,6,7,*, Fanjuan Meng3,*

    Phyton-International Journal of Experimental Botany, Vol.93, No.4, pp. 713-723, 2024, DOI:10.32604/phyton.2024.047657

    Abstract The yield of castor is influenced by the type of inflorescence and the proportion of female flowers. However, there are few studies on the genetic mechanism involved in the development and differentiation of castor inflorescences. In this study, we performed transcriptomic analyses of three different phenotypes of inflorescences at the five-leaf stage. In comparison to the MI (complete pistil without willow leaves), 290 and 89 differentially expressed genes (DEGs) were found in the SFI (complete pistil with willow leaves) and the BI (monoecious inflorescence), respectively. Among the DEGs, 104 and 88 were upregulated in the SFI and BI, respectively, compared… More >

  • Open Access

    ARTICLE

    Mitigating Carbon Emissions: A Comprehensive Analysis of Transitioning to Hydrogen-Powered Plants in Japan’s Energy Landscape Post-Fukushima

    Nugroho Agung Pambudi1,2,4,*, Andrew Chapman, Alfan Sarifudin1,3, Desita Kamila Ulfa4, Iksan Riva Nanda5

    Energy Engineering, Vol.121, No.5, pp. 1143-1159, 2024, DOI:10.32604/ee.2024.047555

    Abstract One of the impacts of the Fukushima disaster was the shutdown of all nuclear power plants in Japan, reaching zero production in 2015. In response, the country started importing more fossil energy including coal, oil, and natural gas to fill the energy gap. However, this led to a significant increase in carbon emissions, hindering the efforts to reduce its carbon footprint. In the current situation, Japan is actively working to balance its energy requirements with environmental considerations, including the utilization of hydrogen fuel. Therefore, this paper aims to explore the feasibility and implications of using hydrogen power plants as a… More >

  • Open Access

    ARTICLE

    A Hybrid Level Set Optimization Design Method of Functionally Graded Cellular Structures Considering Connectivity

    Yan Dong1,2, Kang Zhao1, Liang Gao1, Hao Li1,*

    CMC-Computers, Materials & Continua, Vol.79, No.1, pp. 1-18, 2024, DOI:10.32604/cmc.2024.048870

    Abstract With the continuous advancement in topology optimization and additive manufacturing (AM) technology, the capability to fabricate functionally graded materials and intricate cellular structures with spatially varying microstructures has grown significantly. However, a critical challenge is encountered in the design of these structures–the absence of robust interface connections between adjacent microstructures, potentially resulting in diminished efficiency or macroscopic failure. A Hybrid Level Set Method (HLSM) is proposed, specifically designed to enhance connectivity among non-uniform microstructures, contributing to the design of functionally graded cellular structures. The HLSM introduces a pioneering algorithm for effectively blending heterogeneous microstructure interfaces. Initially, an interpolation algorithm is… More >

  • Open Access

    ARTICLE

    A Novel Foreign Object Detection Method in Transmission Lines Based on Improved YOLOv8n

    Yakui Liu1,2,3,*, Xing Jiang1, Ruikang Xu1, Yihao Cui1, Chenhui Yu1, Jingqi Yang1, Jishuai Zhou1

    CMC-Computers, Materials & Continua, Vol.79, No.1, pp. 1263-1279, 2024, DOI:10.32604/cmc.2024.048864

    Abstract The rapid pace of urban development has resulted in the widespread presence of construction equipment and increasingly complex conditions in transmission corridors. These conditions pose a serious threat to the safe operation of the power grid. Machine vision technology, particularly object recognition technology, has been widely employed to identify foreign objects in transmission line images. Despite its wide application, the technique faces limitations due to the complex environmental background and other auxiliary factors. To address these challenges, this study introduces an improved YOLOv8n. The traditional stepwise convolution and pooling layers are replaced with a spatial-depth convolution (SPD-Conv) module, aiming to… More >

  • Open Access

    ARTICLE

    Anomaly Detection Algorithm of Power System Based on Graph Structure and Anomaly Attention

    Yifan Gao*, Jieming Zhang, Zhanchen Chen, Xianchao Chen

    CMC-Computers, Materials & Continua, Vol.79, No.1, pp. 493-507, 2024, DOI:10.32604/cmc.2024.048615

    Abstract In this paper, we propose a novel anomaly detection method for data centers based on a combination of graph structure and abnormal attention mechanism. The method leverages the sensor monitoring data from target power substations to construct multidimensional time series. These time series are subsequently transformed into graph structures, and corresponding adjacency matrices are obtained. By incorporating the adjacency matrices and additional weights associated with the graph structure, an aggregation matrix is derived. The aggregation matrix is then fed into a pre-trained graph convolutional neural network (GCN) to extract graph structure features. Moreover, both the multidimensional time series segments and… More >

  • Open Access

    ARTICLE

    Efficient Route Planning for Real-Time Demand-Responsive Transit

    Hongle Li1, SeongKi Kim2,*

    CMC-Computers, Materials & Continua, Vol.79, No.1, pp. 473-492, 2024, DOI:10.32604/cmc.2024.048402

    Abstract Demand Responsive Transit (DRT) responds to the dynamic users’ requests without any fixed routes and timetables and determines the stop and the start according to the demands. This study explores the optimization of dynamic vehicle scheduling and real-time route planning in urban public transportation systems, with a focus on bus services. It addresses the limitations of current shared mobility routing algorithms, which are primarily designed for simpler, single origin/destination scenarios, and do not meet the complex demands of bus transit systems. The research introduces an route planning algorithm designed to dynamically accommodate passenger travel needs and enable real-time route modifications.… More >

  • Open Access

    ARTICLE

    HCSP-Net: A Novel Model of Age-Related Macular Degeneration Classification Based on Color Fundus Photography

    Cheng Wan1, Jiani Zhao1, Xiangqian Hong2, Weihua Yang2,*, Shaochong Zhang2,*

    CMC-Computers, Materials & Continua, Vol.79, No.1, pp. 391-407, 2024, DOI:10.32604/cmc.2024.048307

    Abstract Age-related macular degeneration (AMD) ranks third among the most common causes of blindness. As the most conventional and direct method for identifying AMD, color fundus photography has become prominent owing to its consistency, ease of use, and good quality in extensive clinical practice. In this study, a convolutional neural network (CSPDarknet53) was combined with a transformer to construct a new hybrid model, HCSP-Net. This hybrid model was employed to tri-classify color fundus photography into the normal macula (NM), dry macular degeneration (DMD), and wet macular degeneration (WMD) based on clinical classification manifestations, thus identifying and resolving AMD as early as… More >

  • Open Access

    ARTICLE

    A Game-Theoretic Approach to Safe Crowd Evacuation in Emergencies

    Maria Gul1, Imran Ali Khan1, Gohar Zaman2, Atta Rahman3,*, Jamaluddin Mir2, Sardar Asad Ali Biabani4,5, May Issa Aldossary6, Mustafa Youldash7, Ashraf Saadeldeen8, Maqsood Mahmud9, Asiya Abdus Salam6, Dania Alkhulaifi3, Abdullah AlTurkey3

    CMC-Computers, Materials & Continua, Vol.79, No.1, pp. 1631-1657, 2024, DOI:10.32604/cmc.2024.048289

    Abstract Obstacle removal in crowd evacuation is critical to safety and the evacuation system efficiency. Recently, many researchers proposed game theoretic models to avoid and remove obstacles for crowd evacuation. Game theoretical models aim to study and analyze the strategic behaviors of individuals within a crowd and their interactions during the evacuation. Game theoretical models have some limitations in the context of crowd evacuation. These models consider a group of individuals as homogeneous objects with the same goals, involve complex mathematical formulation, and cannot model real-world scenarios such as panic, environmental information, crowds that move dynamically, etc. The proposed work presents… More >

  • Open Access

    ARTICLE

    Infrared and Visible Image Fusion Based on Res2Net-Transformer Automatic Encoding and Decoding

    Chunming Wu1, Wukai Liu2,*, Xin Ma3

    CMC-Computers, Materials & Continua, Vol.79, No.1, pp. 1441-1461, 2024, DOI:10.32604/cmc.2024.048136

    Abstract A novel image fusion network framework with an autonomous encoder and decoder is suggested to increase the visual impression of fused images by improving the quality of infrared and visible light picture fusion. The network comprises an encoder module, fusion layer, decoder module, and edge improvement module. The encoder module utilizes an enhanced Inception module for shallow feature extraction, then combines Res2Net and Transformer to achieve deep-level co-extraction of local and global features from the original picture. An edge enhancement module (EEM) is created to extract significant edge features. A modal maximum difference fusion strategy is introduced to enhance the… More >

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