J. Ryan Mark¹, Leonard G. Gomella¹, Costas D. Lallas¹, Katherine E. Smentkowski¹, Anne Calvaresi¹, Nathan Handley², Robert B. Den³, Patrick Mille², William J. Tester², Jean Hoffman-Censits⁴, Adam P. Dicker³, Edward Klonicke¹, Ethan Halpern⁵, Peter McCue⁵, W. Kevin Kelly², Edouard J. Trabulsi⁶

Canadian Journal of Urology, Vol.30, No.3, pp. 11526-11531, 2023

Abstract Introduction: We report the impact of our 25-year multidisciplinary care delivery model experience on patients with muscle invasive bladder cancer treated at our National Cancer Institute (NCI)-designated Sidney Kimmel Cancer Center at Jefferson University. To our knowledge, our multidisciplinary genitourinary cancer clinic (MDC) is the longest continuously operating center of its kind at an NCI Cancer Center in the United States.
Materials and methods: We selected a recent group of patients with cT2-4 N0-1 M0 bladder cancer seen in the Sidney Kimmel Cancer Center Genitourinary Oncology MDC from January 2016 to September 2019. These patients were identified… More >

Emad Abd Al Rahman¹, Nur Intan Raihana Ruhaiyem^1,*, Majed Bouchahma², Kamarul Imran Musa³

Intelligent Automation & Soft Computing, Vol.36, No.3, pp. 3007-3028, 2023, DOI:10.32604/iasc.2023.032580 - 15 March 2023

Abstract This study offers a framework for a breast cancer computer-aided treatment prediction (CATP) system. The rising death rate among women due to breast cancer is a worldwide health concern that can only be addressed by early diagnosis and frequent screening. Mammography has been the most utilized breast imaging technique to date. Radiologists have begun to use computer-aided detection and diagnosis (CAD) systems to improve the accuracy of breast cancer diagnosis by minimizing human errors. Despite the progress of artificial intelligence (AI) in the medical field, this study indicates that systems that can anticipate a treatment… More >

Fei Wang¹, Jihyun Ma², Nan Zhao³, Chi Lin^3,*, Haixing Jiang^1,*

Oncologie, Vol.24, No.4, pp. 865-895, 2022, DOI:10.32604/oncologie.2022.025447 - 31 December 2022

Abstract Objective: The characteristics of clinical features and prognoses among patients with different racial backgrounds have not been clearly studied. We thus investigated the clinical characteristics and overall survival (OS) differences among Asian, White, and Black patients with pancreatic neuroendocrine tumors (pNETs). Materials and Methods: The Surveillance, Epidemiology, and End Results (SEER) database was queried to identify patients with pNETs between 1983 and 2015. We performed univariable (UVA) and multivariable logistic regression (MVA) to assess the association between variables and race category. A Kaplan-Meier (KM) plot was used to calculate the OS rates. The Cox proportional hazard regression… More >

Stephanie Rodriguez, Andrew D. Sparks, Hanbing Zhou, Richard L. Amdur, Jianqing Lin

Canadian Journal of Urology, Vol.26, No.5, pp. 9946-9951, 2019

Abstract Introduction: To evaluate the impact of prostate cancer screening guidelines on different racial and ethnic populations.
Materials and methods: Data was collected from the 2005-2015 Surveillance, Epidemiology, and End Results (SEER) program. Incidence of prostate cancer diagnosis was categorized and analyzed by stage, race/ethnicity, and age group. Appropriate univariate and multivariable statistical analyses were performed.
Results: The odds of being diagnosed with regional-stage prostate cancer in 2013-2015 were 1.3 times higher for black men, 1.3 times higher for Asian American/Pacific Islander (AAPI) men, and 1.2 times higher for white men when compared to 2005-2008. The odds of being… More >

Michael Daugherty, Dillon Sedaghatpour, Gennady Bratslavsky, Oleg Shapiro

Canadian Journal of Urology, Vol.25, No.4, pp. 9414-9420, 2018

Abstract Introduction: Since the advent of prostate-specific antigen (PSA) screening there has been a decreased incidence of lymph node positive disease (LND). Nevertheless, because of possible upgrading, LND is frequently performed with preoperative Gleason 6 prostate cancer. We utilized the Surveillance Epidemiology and End Results (SEER) database to evaluate the frequency of LND and preoperative variables for node positivity in contemporary patients with preoperative Gleason 6 disease.
Materials and methods: SEER-18 registries database was queried for all patients diagnosed with prostate cancer between the years 2010 and 2014. Patients were excluded that had unknown histology or unknown preoperative… More >

Rachael Sussman^1,2,*, Filipe L.F. Carvalho^1,2,*, Andrew Harbin¹, Choayi Zheng¹, John H. Lynch¹, Lambros Stamatakis², Jonathan Hwang², Stephen B. Williams³, Jim C. Hu⁴, Keith J. Kowalczyk¹

Canadian Journal of Urology, Vol.25, No.5, pp. 9516-9524, 2018

Abstract Introduction: The utility of radical prostatectomy (RP) for locally-advanced prostate cancer remains unknown. Retrospective data has shown equivalent oncologic outcomes compared to radiation therapy (RT). RP may provide local tumor control and prevent secondary interventions from local invasion, and may decrease costs.
Materials and methods: Using SEER-Medicare data from 1995-2011, we identified men with locally-advanced prostate cancer undergoing RP or RT. Rates of post-treatment diagnoses and interventions were identified using ICD-9 and CPT codes. Skeletal related events (SRE), androgen deprivation therapy (ADT) utilization, all-cause mortality, prostate cancer-specific mortality, and costs were compared.
Results: A total of 8367 men… More >